利用超声波润滑实现可变摩擦导管

IF 3.4 Q2 ENGINEERING, BIOMEDICAL
Mostafa A. Atalla;Jeroen J. Tuijp;Michaël Wiertlewski;Aimée Sakes
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引用次数: 0

摘要

微创血管内手术使用导管通过血管进行介入治疗,导管与血管壁之间不可避免地会产生摩擦。虽然这种摩擦增强了介入过程中的稳定性,但也带来了导航过程中损伤血管壁内层的风险,从而导致术后并发症,包括感染性疾病和血栓形成。为了降低不良并发症的风险,我们提出了可变摩擦导管的新概念,这种导管能够在导航过程中从低摩擦力过渡到高摩擦力,从而在进行介入手术时提高稳定性。这种可变摩擦导管利用超声波润滑主动控制导管在手术过程中的摩擦力。在本文中,我们展示了摩擦控制模块的概念验证,该模块是拟议导管设计的关键组件。我们的实验证明,该原型在柔软和坚硬的表面上分别有效减少了 11% 和 60% 的摩擦力,这代表了它在健康组织和钙化组织上的潜在性能。这一结果凸显了设计的可行性及其提高微创血管内手术安全性和有效性的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Toward Variable-Friction Catheters Using Ultrasonic Lubrication
Minimally invasive endovascular procedures use catheters that are guided through blood vessels to perform interventions, resulting in an inevitable frictional interaction between the catheter and the vessel walls. While this friction enhances stability during the intervention, it poses a risk of damaging the inner layer of the blood vessel wall during navigation, leading to post-operative complications including infectious diseases and thrombus formation. To mitigate the risk of adverse complications, we propose a new concept of a variable-friction catheter capable of transitioning from low friction during navigation to high friction for increased stability while performing the intervention. This variable-friction catheter leverages ultrasonic lubrication to actively control the frictional forces experienced by the catheter during the procedure. In this paper, we demonstrate a proof-of-concept for a friction control module, a pivotal component of the proposed catheter design. Our experiments demonstrate that the prototype effectively reduce friction by up to 11% and 60%, on average, on soft and rigid surfaces, representing its potential performance on healthy and calcified tissue, respectively. This result underscores the feasibility of the design and its potential to improve the safety and efficacy of minimally invasive endovascular procedures.
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来源期刊
CiteScore
6.80
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