Junwen Tan, Shipeng Zhang, Yanjie Jiang, Jie Li, Chuan Yang
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The sensitivity analysis validated the analysis's robustness, while publication bias was assessed.</p><p><strong>Results: </strong>The results of the meta-analysis of 14 articles revealed that a plant-based diet (PDI) can reduce cancer mortality (RR = 0.88, [95% CI 0.79-0.98], τ<sup>2</sup>: 0.02, I<sup>2</sup>: 84.71%), cardiovascular disease (CVD) mortality (RR = 0.81, [95% CI 0.76-0.86], τ<sup>2</sup>: 0.00, I<sup>2</sup>: 49.25%) and mortality (RR = 0.84, [95% CI 0.79-0.89], τ<sup>2</sup>: 0.01, I<sup>2</sup>: 81.99%) risk. Adherence to a healthy plant-based diet (hPDI) was negatively correlated with cancer mortality (RR = 0.91, [95% CI 0.83-0.99], τ<sup>2</sup>:0.01, I<sup>2</sup>:85.61%), CVD mortality (RR = 0.85, [95% CI 0.77-0.94], τ<sup>2</sup>: 0.02, I<sup>2</sup>: 85.13%) and mortality (RR = 0.85, [95% CI 0.80-0.90], τ<sup>2</sup>: 0.01, I<sup>2</sup>: 89.83%). An unhealthy plant-based diet (uPDI) was positively correlated with CVD mortality (RR = 1.19, [95% CI 1.07-1.32], τ<sup>2</sup>: 0.02, I<sup>2</sup>: 80.03%) and mortality (RR = 1.18, [95% CI 1.09-1.27], τ<sup>2</sup>: 0.01, I<sup>2</sup>: 89.97%) and had a certain correlation with cancer mortality (RR = 1.10, [95% CI 0.97-1.26], τ<sup>2</sup>: 0.03, I<sup>2</sup>: 93.11%). Sensitivity analysis showed no contradictory results.</p><p><strong>Conclusion: </strong>The hPDI was negatively associated with all-cause mortality, and the uPDI was positively associated with all-cause mortality.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/#loginpage.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1481363"},"PeriodicalIF":4.0000,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537864/pdf/","citationCount":"0","resultStr":"{\"title\":\"Plant-based diet and risk of all-cause mortality: a systematic review and meta-analysis.\",\"authors\":\"Junwen Tan, Shipeng Zhang, Yanjie Jiang, Jie Li, Chuan Yang\",\"doi\":\"10.3389/fnut.2024.1481363\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>A systematic analysis was conducted to determine the relationship between a plant-based diet and all-cause mortality.</p><p><strong>Methods: </strong>The PubMed, Embase and Web of Science databases were searched. 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引用次数: 0
摘要
目的：对植物性饮食与全因死亡率之间的关系进行系统分析：通过系统分析确定植物性饮食与全因死亡率之间的关系：搜索了 PubMed、Embase 和 Web of Science 数据库。两位作者从数据库中选取了英文文献。然后，另外两名作者提取数据，并采用纽卡斯尔-渥太华量表（NOS）进行评估。本研究遵循首选报告项目（PRISMA）指南和 PROSPERO 注册协议。混合效应模型结合了最大调整估计值，并使用 I2 统计量衡量异质性。敏感性分析验证了分析的稳健性，同时对发表偏倚进行了评估：14篇文章的荟萃分析结果显示，植物性饮食（PDI）可降低癌症死亡率（RR = 0.88, [95% CI 0.79-0.98], τ2: 0.02, I2: 84.71%）、心血管疾病（CVD）死亡率（RR = 0.81, [95% CI 0.76-0.86], τ2: 0.00, I2: 49.25%）和死亡率（RR = 0.84, [95% CI 0.79-0.89], τ2: 0.01, I2: 81.99%）风险。坚持以植物为基础的健康饮食（hPDI）与癌症死亡率呈负相关（RR = 0.91，[95% CI 0.83-0.99]，τ2: 0.01，I2: 85.61%）、心血管疾病死亡率（RR = 0.85，[95% CI 0.77-0.94]，τ2：0.02，I2：85.13%）和死亡率（RR = 0.85，[95% CI 0.80-0.90]，τ2：0.01，I2：89.83%）呈负相关。不健康的植物性饮食（uPDI）与心血管疾病死亡率（RR = 1.19，[95% CI 1.07-1.32]，τ2：0.02，I2：80.03%）和死亡率（RR = 1.18，[95% CI 1.09-1.27]，τ2：0.01，I2：89.97%），并与癌症死亡率有一定的相关性（RR = 1.10，[95% CI 0.97-1.26]，τ2：0.03，I2：93.11%）。敏感性分析结果显示没有矛盾之处：hPDI与全因死亡率呈负相关，uPDI与全因死亡率呈正相关。系统综述注册：https://www.crd.york.ac.uk/PROSPERO/#loginpage。
Plant-based diet and risk of all-cause mortality: a systematic review and meta-analysis.
Objective: A systematic analysis was conducted to determine the relationship between a plant-based diet and all-cause mortality.
Methods: The PubMed, Embase and Web of Science databases were searched. Two authors selected English documents from the database. Then the other two authors extracted the data and evaluated the Newcastle-Ottawa Scale (NOS). This study adhered to the guidelines of the Preferred Reporting Project (PRISMA) and the PROSPERO Registry protocols. A mixed-effects model combined maximum adjusted estimates, with heterogeneity measured using the I2 statistic. The sensitivity analysis validated the analysis's robustness, while publication bias was assessed.
Results: The results of the meta-analysis of 14 articles revealed that a plant-based diet (PDI) can reduce cancer mortality (RR = 0.88, [95% CI 0.79-0.98], τ2: 0.02, I2: 84.71%), cardiovascular disease (CVD) mortality (RR = 0.81, [95% CI 0.76-0.86], τ2: 0.00, I2: 49.25%) and mortality (RR = 0.84, [95% CI 0.79-0.89], τ2: 0.01, I2: 81.99%) risk. Adherence to a healthy plant-based diet (hPDI) was negatively correlated with cancer mortality (RR = 0.91, [95% CI 0.83-0.99], τ2:0.01, I2:85.61%), CVD mortality (RR = 0.85, [95% CI 0.77-0.94], τ2: 0.02, I2: 85.13%) and mortality (RR = 0.85, [95% CI 0.80-0.90], τ2: 0.01, I2: 89.83%). An unhealthy plant-based diet (uPDI) was positively correlated with CVD mortality (RR = 1.19, [95% CI 1.07-1.32], τ2: 0.02, I2: 80.03%) and mortality (RR = 1.18, [95% CI 1.09-1.27], τ2: 0.01, I2: 89.97%) and had a certain correlation with cancer mortality (RR = 1.10, [95% CI 0.97-1.26], τ2: 0.03, I2: 93.11%). Sensitivity analysis showed no contradictory results.
Conclusion: The hPDI was negatively associated with all-cause mortality, and the uPDI was positively associated with all-cause mortality.
期刊介绍：
No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health.
Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.
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