急性迷幻药反应、急性期后功能失调态度的变化以及迷幻药相关的幸福感变化。

IF 2.1 4区 医学 Q2 PSYCHOLOGY, CLINICAL
Mitch Earleywine, Genevieve S Falabella, Alyssa B Oliva, Fiona Low
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引用次数: 0

摘要

认知心理疗法的基石--功能失调态度--会随着心理和药物干预而变化。这些认知的急性期后变化似乎与对迷幻药的急性期反应有关,而这种反应往往发生在疗效改善之前。对功能失调态度的急性期后变化进行研究,可以支持在迷幻药辅助治疗中将其作为治疗目标。经过筛选的参与者(N = 400+)报告了与他们最显著的迷幻反应相关的急性主观体验,以及功能失调态度的急性期后变化和随后的幸福感改变。功能失调态度、情感突破和挑战性体验在幸福感方面造成了显著而独特的差异。机能障碍态度的影响通常超过急性反应的影响。对这些急性反应进行比较后发现,情感突破的影响超过了挑战性体验,而挑战性体验又超过了神秘体验。然而,功能失调态度在急性期后的变化所产生的间接效应并不能完全解释急性期效应的影响,也不能与急性期效应相互影响。这些结果强调了急性反应和急性期后反应的重要性,表明优化这两种反应的策略可能会使迷幻药辅助干预的效果最大化。此外,改变这些认知的标准认知干预措施可以直接与迷幻药相结合。研究结果还支持使用多种多元方法来解决多重共线预测因素的相对重要性问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acute Psychedelic Reactions, Post-Acute Changes in Dysfunctional Attitudes, and Psychedelic-Associated Changes in Wellbeing.

Dysfunctional attitudes - a cornerstone to cognitive psychotherapy - vary with both psychological and pharmacological interventions. Post-acute changes in these cognitions appear to covary with the acute reactions to psychedelics that often precede improved outcomes. An examination of post-acute changes in dysfunctional attitudes could support targeting them in psychedelic-assisted therapy. Screened participants (N = 400+) reported the acute, subjective experiences associated with their most significant psychedelic response as well as post-acute changes in dysfunctional attitudes and subsequent alterations in wellbeing. Dysfunctional attitudes, emotional breakthroughs, and challenging experiences accounted for significant, unique variance in wellbeing. The effects of dysfunctional attitudes generally exceeded those of acute reactions. Comparisons among those acute responses revealed that the effect of emotional breakthroughs exceeded challenging experiences, which exceeded mystical experiences. Nevertheless, the indirect effects through post-acute changes in dysfunctional attitudes did not account for all the impact of acute effects nor interact with them. These results emphasize the import of both acute and post-acute reactions, suggesting that strategies for optimizing each might maximize outcomes for psychedelic-assisted interventions. Furthermore, standard cognitive interventions that alter these cognitions could combine with psychedelics in straightforward ways. The results also support the use of multiple multivariate approaches to address the relative importance of multicollinear predictors.

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来源期刊
CiteScore
5.30
自引率
7.10%
发文量
62
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