金属-电介质混合超表面的强耦合诱导超灵敏手性探测

IF 4.6 2区物理与天体物理 Q1 OPTICS

Optics and Laser Technology Pub Date : 2024-10-23 DOI:10.1016/j.optlastec.2024.111995

Tianxu Jia , Bingjue Li , Bing Gu , Qiwen Zhan , Guanghao Rui

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引用次数: 0

摘要

由于光吸收的限制，圆二色性（CD）光谱难以检测到手性小分子的微弱信号。本研究介绍了一种利用金属-电介质混合元表面显著增强 CD 信号的方法。元表面会产生一个超手性热点，从而放大附近分子的手性。该方法提出了两种技术来克服本征信号和诱导信号之间的信号抵消，从而使 CD 信号的整体增强高达 23,630 倍。这种方法具有在纳米尺度上超灵敏检测手性分子的潜力，可应用于药理学、毒理学和生命科学领域。

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Strong coupling induced ultrasensitive chiral detection by metal-dielectric hybrid metasurface

Circular dichroism (CD) spectroscopy struggles to detect weak signals from small, chiral molecules due to limitations in light absorption. This study introduces a method for significantly enhancing CD signals using a metal-dielectric hybrid metasurface. The metasurface creates a superchiral hotspot that amplifies the chirality of nearby molecules. Two techniques are proposed to overcome signal cancellation between the intrinsic and induced signals to achieve an overall enhancement of the CD signal by up to 23,630 times. This approach has the potential for ultrasensitive detection of chiral molecules at the nanoscale, with applications in pharmacology, toxicology, and life sciences.

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来源期刊

Optics and Laser Technology 物理-光学

CiteScore

8.50

自引率

10.00%

发文量

1060

审稿时长

3.4 months

期刊介绍： Optics & Laser Technology aims to provide a vehicle for the publication of a broad range of high quality research and review papers in those fields of scientific and engineering research appertaining to the development and application of the technology of optics and lasers. Papers describing original work in these areas are submitted to rigorous refereeing prior to acceptance for publication. The scope of Optics & Laser Technology encompasses, but is not restricted to, the following areas: •development in all types of lasers •developments in optoelectronic devices and photonics •developments in new photonics and optical concepts •developments in conventional optics, optical instruments and components •techniques of optical metrology, including interferometry and optical fibre sensors •LIDAR and other non-contact optical measurement techniques, including optical methods in heat and fluid flow •applications of lasers to materials processing, optical NDT display (including holography) and optical communication •research and development in the field of laser safety including studies of hazards resulting from the applications of lasers (laser safety, hazards of laser fume) •developments in optical computing and optical information processing •developments in new optical materials •developments in new optical characterization methods and techniques •developments in quantum optics •developments in light assisted micro and nanofabrication methods and techniques •developments in nanophotonics and biophotonics •developments in imaging processing and systems