Michael Hawrylycz, Eitan S. Kaplan, Kyle J. Travaglini, Mariano I. Gabitto, Jeremy A. Miller, Lydia Ng, Jennie L. Close, Rebecca D. Hodge, Brian Long, Tyler Mollenkopf, Shoaib Mufti, Nicole M. Gatto, Eric B. Larson, Paul K. Crane, Thomas J. Grabowski, C. Dirk Keene, Ed S. Lein
{"title":"SEA-AD 是阿尔茨海默病的多模态细胞图谱和资源","authors":"Michael Hawrylycz, Eitan S. Kaplan, Kyle J. Travaglini, Mariano I. Gabitto, Jeremy A. Miller, Lydia Ng, Jennie L. Close, Rebecca D. Hodge, Brian Long, Tyler Mollenkopf, Shoaib Mufti, Nicole M. Gatto, Eric B. Larson, Paul K. Crane, Thomas J. Grabowski, C. Dirk Keene, Ed S. Lein","doi":"10.1038/s43587-024-00719-8","DOIUrl":null,"url":null,"abstract":"The Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD) is a multifaceted open-data resource that is designed to identify cellular and molecular pathologies that underlie Alzheimer’s disease. Integrating neuropathology, single-cell and spatial genomics, and longitudinal clinical metadata, SEA-AD is a unique resource for studying the pathogenesis of Alzheimer’s disease and related dementias.","PeriodicalId":94150,"journal":{"name":"Nature aging","volume":"4 10","pages":"1331-1334"},"PeriodicalIF":17.0000,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"SEA-AD is a multimodal cellular atlas and resource for Alzheimer’s disease\",\"authors\":\"Michael Hawrylycz, Eitan S. Kaplan, Kyle J. Travaglini, Mariano I. Gabitto, Jeremy A. Miller, Lydia Ng, Jennie L. Close, Rebecca D. Hodge, Brian Long, Tyler Mollenkopf, Shoaib Mufti, Nicole M. Gatto, Eric B. Larson, Paul K. Crane, Thomas J. Grabowski, C. Dirk Keene, Ed S. Lein\",\"doi\":\"10.1038/s43587-024-00719-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD) is a multifaceted open-data resource that is designed to identify cellular and molecular pathologies that underlie Alzheimer’s disease. Integrating neuropathology, single-cell and spatial genomics, and longitudinal clinical metadata, SEA-AD is a unique resource for studying the pathogenesis of Alzheimer’s disease and related dementias.\",\"PeriodicalId\":94150,\"journal\":{\"name\":\"Nature aging\",\"volume\":\"4 10\",\"pages\":\"1331-1334\"},\"PeriodicalIF\":17.0000,\"publicationDate\":\"2024-10-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature aging\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s43587-024-00719-8\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature aging","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43587-024-00719-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
SEA-AD is a multimodal cellular atlas and resource for Alzheimer’s disease
The Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD) is a multifaceted open-data resource that is designed to identify cellular and molecular pathologies that underlie Alzheimer’s disease. Integrating neuropathology, single-cell and spatial genomics, and longitudinal clinical metadata, SEA-AD is a unique resource for studying the pathogenesis of Alzheimer’s disease and related dementias.