使用 COMSOL 对三叶主动脉瓣进行流体-结构相互作用模拟。

IF 1.7 4区医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS

Computer Methods in Biomechanics and Biomedical Engineering Pub Date : 2024-10-01 DOI:10.1080/10255842.2024.2410226

Xiaoyang Xu, Jie Cheng

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引用次数: 0

摘要

由于主动脉瓣（AV）的几何复杂性和问题的多物理特性，其仿真仍然具有挑战性。在这项研究中，我们利用 COMSOL 建立了一个三维三叶主动脉瓣流固耦合模型，并研究了健康状态下材料特性对瓣膜机械行为的影响。结果表明，主动脉壁材料模型的变化对房室血流动力学的影响较小。此外，虽然瓣叶的线性弹性特性限制了瓣膜的打开和关闭，但这种材料模型可以在材料变形范围内快速评估房室的性能。

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Fluid-structure interaction simulation of the three-leaflet aortic valve using COMSOL.

The simulation of the aortic valve (AV) remains challenging due to its geometric complexity and the multi-physics nature of the problem. In this study, we utilized COMSOL to establish a three-dimensional, three-leaflet AV fluid-structure interaction model and investigated the influence of material properties on the valve's mechanical behavior in a healthy state. The results indicated that variations in the aortic wall material model had a minor impact on AV hemodynamics. Additionally, while the linear elastic properties of the leaflets limit valve opening and closing, this material model allows for rapid assessment of AV performance within the range of material deformation.

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来源期刊

Computer Methods in Biomechanics and Biomedical Engineering 工程技术-工程：生物医学

CiteScore

4.10

自引率

6.20%

发文量

179

审稿时长

4-8 weeks

期刊介绍： The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.