不同运动量与糖尿病前期成人罹患 2 型糖尿病的风险：一项基于人群的队列研究。

IF 4.4 2区医学 Q1 NUTRITION & DIETETICS

Nutrition Journal Pub Date : 2024-09-17 DOI:10.1186/s12937-024-01013-4

Wenchang Yang, Yuntao Wu, Yue Chen, Shuohua Chen, Xiang Gao, Shouling Wu, Liang Sun

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引用次数: 0

摘要

研究目的本研究旨在评估不同体力活动水平与中国成年糖尿病前期患者罹患2型糖尿病（T2D）风险之间的关系：这项前瞻性人群队列研究纳入了开滦研究2014年调查的12424名糖尿病前期患者（平均[标码]年龄为52.8[16.8]岁；82.2%为男性）。体力活动信息通过国际体力活动问卷-简表收集，并按任务的代谢当量（MET）分为低、中、高三类。通过建立考克斯回归模型来估算体力活动水平与T2D发病率之间的危险比（HRs）和95%置信区间（CIs）：中位随访 3.6 年期间，2207 名参与者（17.8%）患上了 T2D。低、中、高体力活动水平组的 T2D 发生率分别为 55.83/1000、35.14/1000 和 39.61/1000。与低体力活动水平相比，中等体力活动水平（HR 0.57，95% CI 0.49 至 0.67）和高体力活动水平（HR 0.76，95% CI 0.66 至 0.89）与较低的 T2D 发病风险相关（P 为趋势结论）：这项研究表明，糖尿病前期患者可从中度和高度的体育锻炼中获益。

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Different levels of physical activity and risk of developing type 2 diabetes among adults with prediabetes: a population-based cohort study.

Objectives: This study aimed to evaluate the association between different levels of physical activity and risk of developing type 2 diabetes (T2D) mellitus among adults with prediabetes in Chinese population.

Methods: This prospective population-based cohort study included 12,424 participants (mean [SD] age, 52.8 [16.8] years; 82.2% men) with prediabetes at 2014 survey of the Kailuan study. Physical activity information was collected through the International Physical Activity Questionnaire-Short Form and categorized by metabolic equivalent (MET) of task as low, moderate, and high. Cox regression models were built to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for associations between physical activity levels and incident T2D.

Results: During a median follow-up of 3.6 years, 2,207 (17.8%) participants developed T2D. The incident rate of T2D were 55.83/1000, 35.14/1000, and 39.61/1000 person-years in the low, moderate, and high physical activity level group, respectively. Both moderate (HR 0.57, 95% CI 0.49 to 0.67) and high (HR 0.76, 95% CI 0.66 to 0.89) physical activity levels were associated with lower risks of developing T2D compared to low physical activity level (P for trend < 0.001). The association between high physical activity level and T2D was primarily observed in participants without metabolic syndrome (P for interaction < 0.001). Moreover, participants with moderate or high levels of physical activity had significantly decreased fasting blood glucose levels during follow-up when compared to those with low level (P group*time < 0.001).

Conclusion: This study suggested that individuals with prediabetes might benefit from moderate and high levels of physical activity.

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来源期刊

Nutrition Journal NUTRITION & DIETETICS-

CiteScore

9.80

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Nutrition Journal publishes surveillance, epidemiologic, and intervention research that sheds light on i) influences (e.g., familial, environmental) on eating patterns; ii) associations between eating patterns and health, and iii) strategies to improve eating patterns among populations. The journal also welcomes manuscripts reporting on the psychometric properties (e.g., validity, reliability) and feasibility of methods (e.g., for assessing dietary intake) for human nutrition research. In addition, study protocols for controlled trials and cohort studies, with an emphasis on methods for assessing dietary exposures and outcomes as well as intervention components, will be considered. Manuscripts that consider eating patterns holistically, as opposed to solely reductionist approaches that focus on specific dietary components in isolation, are encouraged. Also encouraged are papers that take a holistic or systems perspective in attempting to understand possible compensatory and differential effects of nutrition interventions. The journal does not consider animal studies. In addition to the influence of eating patterns for human health, we also invite research providing insights into the environmental sustainability of dietary practices. Again, a holistic perspective is encouraged, for example, through the consideration of how eating patterns might maximize both human and planetary health.