术中壁龛涂片中颗粒细胞胶质母细胞瘤的细胞病理学发现：病例报告

IF 1.2 4区医学 Q4 CELL BIOLOGY

Cytopathology Pub Date : 2024-09-13 DOI:10.1111/cyt.13442

Samuel López‐Muñoz, Borja Sánchez‐Cordon, Mario Taravilla‐Loma, Isabel Esteban‐Rodríguez

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引用次数: 0

摘要

颗粒细胞胶质母细胞瘤是IDH-野生型胶质母细胞瘤的一种罕见亚型，在术中会诊时可能与富含巨噬细胞的良性脑病变相似。此前很少有研究讨论其细胞病理学特征，并特别关注术中会诊时的鉴别诊断。在对以前报道的病例进行比较分析后，我们发现一些细胞病理学发现有助于将颗粒状肿瘤细胞与巨噬细胞和其他中枢神经系统肿瘤相鉴别，尽管它们的表现形式并不固定，临床和放射学相关性始终是至关重要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cytopathological findings of granular cell glioblastoma in intraoperative squash smear preparations: A case report

Granular cell glioblastoma is a rare subtype of IDH‐wildtype glioblastoma, which may mimic benign macrophage‐rich brain lesions during intraoperative consultation. Few studies have previously discussed its cytopathological features with special attention to the differential diagnosis during intraoperative consultation. After a comparative analysis of previously reported cases, we found that some cytopathological findings can be useful to differentiate granular tumour cells from macrophages and other central nervous system tumours, although their presentation is not constant and clinical and radiological correlation is always critical.

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来源期刊

Cytopathology 生物-病理学

CiteScore

2.30

自引率

15.40%

发文量

107

审稿时长

6-12 weeks

期刊介绍： The aim of Cytopathology is to publish articles relating to those aspects of cytology which will increase our knowledge and understanding of the aetiology, diagnosis and management of human disease. It contains original articles and critical reviews on all aspects of clinical cytology in its broadest sense, including: gynaecological and non-gynaecological cytology; fine needle aspiration and screening strategy. Cytopathology welcomes papers and articles on: ultrastructural, histochemical and immunocytochemical studies of the cell; quantitative cytology and DNA hybridization as applied to cytological material.