皮层下失语症:最新进展

IF 5.4 3区 材料科学 Q2 CHEMISTRY, PHYSICAL
Victor Nascimento Almeida, Marcia Radanovic
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引用次数: 0

摘要

本综述旨在重新讨论有关基底节和丘脑在传统神经影像学研究评估的皮质语言区域未发生严重解剖学病变的情况下,在失语症状的形成过程中所起作用的主要理论。语言加工的新概念和现代神经影像学技术在解决目前主流理论之间的僵局方面取得了一些进展:(a) 直接和特定的语言加工和 (b) 皮层下结构作为一般领域功能的加工中继。基于功能性磁共振成像(MRI)和磁束成像(tra tractography)的连通性研究尤为引人关注,这些研究强调了白质通路病变对失语症发展和恢复的影响。至于丘脑,其通过调节额叶皮层参与词汇语义处理的作用正变得越来越明显。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Subcortical Aphasia: An Update

Subcortical Aphasia: An Update

Purpose of review

This review aims to rediscuss the leading theories concerning the role of basal ganglia and the thalamus in the genesis of aphasic symptoms in the absence of gross anatomical lesions in cortical language areas as assessed by conventional neuroimaging studies.

Recent findings

New concepts in language processing and modern neuroimaging techniques have enabled some progress in resolving the impasse between the current dominant theories: (a) direct and specific linguistic processing and (b) subcortical structures as processing relays in domain-general functions. Of particular interest are studies of connectivity based on functional magnetic resonance imaging (MRI) and tractography that highlight the impact of white matter pathway lesions on aphasia development and recovery.

Summary

Connectivity studies have put into evidence the central role of the arcuate fasciculus (AF), inferior frontal occipital fasciculus (IFOF), and uncinate fasciculus (UF) in the genesis of aphasia. Regarding the thalamus, its involvement in lexical-semantic processing through modulation of the frontal cortex is becoming increasingly apparent.

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来源期刊
ACS Applied Energy Materials
ACS Applied Energy Materials Materials Science-Materials Chemistry
CiteScore
10.30
自引率
6.20%
发文量
1368
期刊介绍: ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.
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