用于高灵敏无标记生物传感的新型双栅负电容 TFET

IF 1.9 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC
Ravindra Kumar Maurya, Radhe Gobinda Debnath, Ajeet Kumar Yadav, Brinda Bhowmick
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引用次数: 0

摘要

负电容(NC)隧道场效应晶体管(NCTFET)是开发高灵敏度生物传感器的可行选择。本研究在 NCTFET 中引入了双栅 (DG) 结构和 n+ 掺杂袋,以提高生物传感器的性能和灵敏度。本研究对两种生物传感器设计进行了全面的比较分析:DG-NCTFET 和掺杂 n+ 口袋的 DG-NCTFET。这两种生物传感器都在固定电介质的两侧设置了纳米间隙,从而扩大了生物分子捕获区域。灵敏度评估考虑了介电常数(k)范围内的带电和中性生物分子。n+ 袋 DG-NCTFET 的离子灵敏度大约是无袋传感器的 20 倍(n+ 袋 DG-NCTFET 为 3.5 × 106,DG-NCTFET 为 1.8 × 105),这主要是因为它能在垂直和横向两个方向上传导电流。此外,对于完全填充了中性生物分子的纳米腔体,n+ 袋 DG-NCTFET 和传统 DG-NCTFET 所达到的最大 ION/IOFF 灵敏度分别为 1.2 × 105 和 2.8 × 104。此外,这项研究还深入探讨了立体阻碍和探针不规则放置的影响,旨在掌握传感器表现出的非理想特性。值得注意的是,当填充因子从 40% 提升到 66% 时,灵敏度会有大约 6%-11% 的微弱增长。为了设定一个比较标准,根据灵敏度方面的现有文献,对拟议的生物传感器进行了基准测试,以肯定其功效。研究结果表明,所提出的生物传感器是检测各种带电和中性生物分子的理想选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A novel dual-gate negative capacitance TFET for highly sensitive label free biosensing
The negative capacitance (NC) tunnel FET (NCTFET) emerges as a viable choice for the development of highly sensitive biosensors. A dual-gate (DG) structure and n+ doped pocket within the NCTFET is introduced in this study to boost biosensor performance and sensitivity. This research offers a comprehensive and comparative analysis of two biosensor designs: the DG-NCTFET and the n+ pocket-doped DG-NCTFET. Both biosensors feature nanogaps on either side of the fixed dielectric, augmenting their biomolecule capture areas. Sensitivity assessments are conducted considering charged and neutral biomolecules with a range of dielectric constants (k). The n+ pocket DG-NCTFET exhibits an ION sensitivity roughly 20 times greater than that of the sensor without a pocket (3.5 × 106 for n+ pocket DG-NCTFET and 1.8 × 105 for DG-NCTFET), primarily because it conducts current in both vertical and lateral directions. Furthermore, for fully filled nanocavity with neutral biomolecules, the maximum ION/IOFF sensitivities attained are 1.2 × 105 and 2.8 × 104 for the n+ pocket DG-NCTFET and conventional DG-NCTFET, respectively. Moreover, this research delves into the impact of steric hindrance and the irregular placement of probes, aiming to grasp the non-ideal traits exhibited by the sensors. Significantly, sensitivity experiences a minimal increase of approximately 6%–11% when the fill factor escalates from 40% to 66%. In order to set a standard of comparison, the proposed biosensors are benchmarked against existing literature in terms of sensitivity, affirming their efficacy. The findings indicate that the proposed biosensors represent a promising alternative for detecting a wide range of both charged and neutral biomolecules.
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来源期刊
Semiconductor Science and Technology
Semiconductor Science and Technology 工程技术-材料科学:综合
CiteScore
4.30
自引率
5.30%
发文量
216
审稿时长
2.4 months
期刊介绍: Devoted to semiconductor research, Semiconductor Science and Technology''s multidisciplinary approach reflects the far-reaching nature of this topic. The scope of the journal covers fundamental and applied experimental and theoretical studies of the properties of non-organic, organic and oxide semiconductors, their interfaces and devices, including: fundamental properties materials and nanostructures devices and applications fabrication and processing new analytical techniques simulation emerging fields: materials and devices for quantum technologies hybrid structures and devices 2D and topological materials metamaterials semiconductors for energy flexible electronics.
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