青少年女性上肢色素性瘙痒症的罕见病例：罕见病例。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-03 DOI:10.1111/pde.15731

Gökçe Işıl Kurmuş, Laden Elkıran, Dilek Menteşoğlu, Ebru Şebnem Ayva, Selda Pelin Kartal

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引用次数: 0

摘要

一名 16 岁的女孩在开始摄入生酮饮食后患上了色素性瘙痒症（PP），表现为上肢瘙痒、红斑和褐色丘疹。组织病理学检查发现，轻度海绵状增生，血管周围有中性粒细胞和单核细胞浸润，确诊为 PP。口服多西环素并停止生酮饮食治疗后，皮损在一个月内消退，但随后出现炎症后色素沉着。该病例凸显了 PP 仅出现在儿童患者上肢的罕见性，拓展了我们对这种皮肤病的认识。

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Unusual case of prurigo pigmentosa on the upper extremities in an adolescent female: A rare presentation.

A 16-year-old girl developed prurigo pigmentosa (PP) following initiation of a ketogenic diet, presenting with pruritic, erythematous, and brownish papules exclusively on her upper extremities. Histopathological examination revealed mild spongiosis with perivascular neutrophilic and mononuclear cell infiltrate, confirming the diagnosis of PP. Treatment with oral doxycycline and discontinuation of the ketogenic diet led to lesion resolution within one month, with subsequent postinflammatory hyperpigmentation. This case highlights the rarity of PP presenting solely on the upper extremities in pediatric patients, expanding our understanding of this dermatological disease.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.