生物活性多糖的多重益处:从肠道到整体健康

IF 15.1 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY
Renzhi Huang , Jia Zhang , Xinxin Xu , Maozhong Sun , Liguang Xu , Hua Kuang , Chuanlai Xu , Lingling Guo
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引用次数: 0

摘要

背景活性多糖是从天然物质中提取的一类重要活性成分,可用于食品、医药和保健领域。作为一种天然的肠道微生态调节剂,活性多糖以其来源丰富、药效稳定、副作用小等特点,被广泛应用于肠道微生态、肠道肿瘤和肠道炎症的调节。随着活性多糖越来越多地用于各种肠道相关疾病的治疗研究,探讨其对肠道和生物体健康的影响也变得越来越重要。范围和方法本综述主要研究多糖的单糖组成、糖苷键类型和分子量大小对生物体的影响,为食品和药物开发提供理论依据。综述了活性多糖对肠道微生物群、机械屏障、免疫屏障和粘液屏障的调节作用,并讨论了活性多糖在宿主体内的作用机制。此外,本综述还阐述了活性多糖对机体健康的影响,包括增强抗氧化和免疫系统功能、抗肿瘤和消炎作用、调节血糖和血脂水平等。主要发现和结论活性多糖在食品和药物领域具有广阔的应用前景,因此本综述通过介绍活性多糖用于维护肠道健康领域的最新研究及其对机体整体健康的保护作用,为食品和药物开发提供了新思路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The multiple benefits of bioactive polysaccharides: From the gut to overall health

Background

Active polysaccharides are a class of important active ingredients extracted from natural substances, which are used in the fields of food, medicine and health care. As a natural intestinal microecological regulator, active polysaccharides are widely used to regulate intestinal microecology, intestinal tumors, and intestinal inflammation due to their abundant availability, stable efficacy, and few side effects. With the increasing use of active polysaccharides in therapeutic studies for a variety of gut-related diseases, it is increasingly important to explore their effects on gut and organismal health.

Scope and approach

This review focuses on the effects of the monosaccharide composition of polysaccharides, the type of glycosidic bonding, and molecular weight size on organisms, providing a theoretical basis for food and drug development. The modulatory effects of active polysaccharides on the gut microbiota, mechanical barriers, immune barriers, and mucus barriers are summarized, and the mechanisms of action of active polysaccharides in the host are discussed. In addition, this review describes the effects of active polysaccharides on the health of the body, including enhancement of antioxidant and immune system function, antitumor and inflammation-reducing effects, and blood glucose and lipid level regulation.

Key founds and conclusion

Active polysaccharides have a broad application prospect in the food and drug field, so this review provides new ideas for food and drug development by presenting the latest research in the field of active polysaccharides use to maintain intestinal health and their protective effect on the overall health of the organism.

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来源期刊
Trends in Food Science & Technology
Trends in Food Science & Technology 工程技术-食品科技
CiteScore
32.50
自引率
2.60%
发文量
322
审稿时长
37 days
期刊介绍: Trends in Food Science & Technology is a prestigious international journal that specializes in peer-reviewed articles covering the latest advancements in technology, food science, and human nutrition. It serves as a bridge between specialized primary journals and general trade magazines, providing readable and scientifically rigorous reviews and commentaries on current research developments and their potential applications in the food industry. Unlike traditional journals, Trends in Food Science & Technology does not publish original research papers. Instead, it focuses on critical and comprehensive reviews to offer valuable insights for professionals in the field. By bringing together cutting-edge research and industry applications, this journal plays a vital role in disseminating knowledge and facilitating advancements in the food science and technology sector.
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