{"title":"通过厌氧微生物工艺利用低成本可再生资源生产乳酸的生物技术。","authors":"Andriy Anta Kacaribu, Darwin","doi":"10.5114/bta.2024.139757","DOIUrl":null,"url":null,"abstract":"<p><p>Lactic acid (LA) production from microbial fermentation using low-cost renewable sources has emerged as an attractive alternative to the use of petroleum-based products. This approach not only offers sustainable solutions for waste management but also enables the production of value-added products in an eco-friendly manner. However, to make this approach economically viable, optimizing the production process for high yield, productivity, and purity while minimizing costs is crucial. To address these challenges, various approaches have been proposed, including the use of neutralizing agents, high cell density cultures, co-cultures, fed-batch fermentation, and product removal strategies. Overall, this review underscores the potential of microbial fermentation for LA production as a sustainable and cost-effective solution to meet the growing demand for eco-friendly products. Further optimization of fermentation processes and the development of new microbial strains and fermentation techniques are key to advancing this approach. The production of LA through microbial fermentation presents a sustainable and eco-friendly solution to the increasing demand for eco-friendly products. With continued innovation, we can expect to see a significant reduction in the environmental impact of industrial processes, coupled with a more cost-effective and high-purity source of lactic acid for various industries.</p>","PeriodicalId":94371,"journal":{"name":"Biotechnologia","volume":"105 2","pages":"179-194"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232001/pdf/","citationCount":"0","resultStr":"{\"title\":\"Biotechnological lactic acid production from low-cost renewable sources <i>via</i> anaerobic microbial processes.\",\"authors\":\"Andriy Anta Kacaribu, Darwin\",\"doi\":\"10.5114/bta.2024.139757\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Lactic acid (LA) production from microbial fermentation using low-cost renewable sources has emerged as an attractive alternative to the use of petroleum-based products. This approach not only offers sustainable solutions for waste management but also enables the production of value-added products in an eco-friendly manner. However, to make this approach economically viable, optimizing the production process for high yield, productivity, and purity while minimizing costs is crucial. To address these challenges, various approaches have been proposed, including the use of neutralizing agents, high cell density cultures, co-cultures, fed-batch fermentation, and product removal strategies. Overall, this review underscores the potential of microbial fermentation for LA production as a sustainable and cost-effective solution to meet the growing demand for eco-friendly products. Further optimization of fermentation processes and the development of new microbial strains and fermentation techniques are key to advancing this approach. The production of LA through microbial fermentation presents a sustainable and eco-friendly solution to the increasing demand for eco-friendly products. With continued innovation, we can expect to see a significant reduction in the environmental impact of industrial processes, coupled with a more cost-effective and high-purity source of lactic acid for various industries.</p>\",\"PeriodicalId\":94371,\"journal\":{\"name\":\"Biotechnologia\",\"volume\":\"105 2\",\"pages\":\"179-194\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232001/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biotechnologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5114/bta.2024.139757\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biotechnologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/bta.2024.139757","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
利用低成本的可再生资源通过微生物发酵生产乳酸(LA)已成为使用石油产品的一种有吸引力的替代品。这种方法不仅为废物管理提供了可持续的解决方案,还能以生态友好的方式生产增值产品。然而,要使这种方法在经济上可行,就必须优化生产工艺,以提高产量、生产率和纯度,同时最大限度地降低成本。为应对这些挑战,人们提出了各种方法,包括使用中和剂、高细胞密度培养、共培养、饲料批量发酵和产品去除策略。总之,本综述强调了微生物发酵生产 LA 的潜力,它是一种可持续的、具有成本效益的解决方案,可满足人们对环保产品日益增长的需求。进一步优化发酵过程、开发新的微生物菌株和发酵技术是推进这种方法的关键。通过微生物发酵生产 LA 是一种可持续的生态友好型解决方案,可满足对生态友好型产品日益增长的需求。随着不断创新,我们有望看到工业流程对环境的影响显著降低,同时为各行各业提供更具成本效益的高纯度乳酸来源。
Biotechnological lactic acid production from low-cost renewable sources via anaerobic microbial processes.
Lactic acid (LA) production from microbial fermentation using low-cost renewable sources has emerged as an attractive alternative to the use of petroleum-based products. This approach not only offers sustainable solutions for waste management but also enables the production of value-added products in an eco-friendly manner. However, to make this approach economically viable, optimizing the production process for high yield, productivity, and purity while minimizing costs is crucial. To address these challenges, various approaches have been proposed, including the use of neutralizing agents, high cell density cultures, co-cultures, fed-batch fermentation, and product removal strategies. Overall, this review underscores the potential of microbial fermentation for LA production as a sustainable and cost-effective solution to meet the growing demand for eco-friendly products. Further optimization of fermentation processes and the development of new microbial strains and fermentation techniques are key to advancing this approach. The production of LA through microbial fermentation presents a sustainable and eco-friendly solution to the increasing demand for eco-friendly products. With continued innovation, we can expect to see a significant reduction in the environmental impact of industrial processes, coupled with a more cost-effective and high-purity source of lactic acid for various industries.