Lukky Jayadi, Sandry Kesuma, Muhammad Hasan Wattiheluw, Elok Widayanti, Nurma Sabila, Hanandayu Widwiastuti, Riska Yudhistia Asworo, Retno Ikayanti
{"title":"香茅草(Cymbopogon nardus L.)精油提取物固体肥皂制剂的配制及其对李斯特菌的作用","authors":"Lukky Jayadi, Sandry Kesuma, Muhammad Hasan Wattiheluw, Elok Widayanti, Nurma Sabila, Hanandayu Widwiastuti, Riska Yudhistia Asworo, Retno Ikayanti","doi":"10.46542/pe.2024.242.3238","DOIUrl":null,"url":null,"abstract":"Background: The components of essential oils, such as citronellol, citronellal, and geraniol have been reported to possess the ability to inhibit bacteria. Furthermore, Listeria monocytogenes is a bacteria that often affects humans and its infections can cause meningitis and bacteremia. In pregnant women, Listeria monocytogenes can cause flu-like syndrome with complications of miscarriage, infant death, and meningitis in infants. \nObjective: This study evaluated the suitability of solid soap preparations from Citronella grass essential oil, based on its physical properties, such as organoleptic tests, as well as assessments of chemical tests and the effectiveness of the sample produced against bacteria. \nMethod: The soap-making process was initiated by mixing the fat fraction (stearic acid and coconut oil) with an alkali, namely 30% NaOH. The soap stock was then added to the other ingredients and stirred until it became homogeneous for testing. \nResults: The test showed a pH value, water content, total fat, ethanol insoluble material, free fatty acids, chloride content, and unsaponificable fat of 10.8, 14.26, 74.84, 2.4, 0.26, 0.48, and 85.8, respectively. Furthermore, the sample showed a high level of inhibition against Listeria monocytogenes. \nConclusion: Evaluation of citronella essential oil extract soap met the requirements, except for its unsaponifiable fat.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Formulation and effectiveness of solid soap preparations from citronella grass (Cymbopogon nardus L.) essential oil extract against Listeria monocytogenes\",\"authors\":\"Lukky Jayadi, Sandry Kesuma, Muhammad Hasan Wattiheluw, Elok Widayanti, Nurma Sabila, Hanandayu Widwiastuti, Riska Yudhistia Asworo, Retno Ikayanti\",\"doi\":\"10.46542/pe.2024.242.3238\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: The components of essential oils, such as citronellol, citronellal, and geraniol have been reported to possess the ability to inhibit bacteria. Furthermore, Listeria monocytogenes is a bacteria that often affects humans and its infections can cause meningitis and bacteremia. In pregnant women, Listeria monocytogenes can cause flu-like syndrome with complications of miscarriage, infant death, and meningitis in infants. \\nObjective: This study evaluated the suitability of solid soap preparations from Citronella grass essential oil, based on its physical properties, such as organoleptic tests, as well as assessments of chemical tests and the effectiveness of the sample produced against bacteria. \\nMethod: The soap-making process was initiated by mixing the fat fraction (stearic acid and coconut oil) with an alkali, namely 30% NaOH. The soap stock was then added to the other ingredients and stirred until it became homogeneous for testing. \\nResults: The test showed a pH value, water content, total fat, ethanol insoluble material, free fatty acids, chloride content, and unsaponificable fat of 10.8, 14.26, 74.84, 2.4, 0.26, 0.48, and 85.8, respectively. Furthermore, the sample showed a high level of inhibition against Listeria monocytogenes. \\nConclusion: Evaluation of citronella essential oil extract soap met the requirements, except for its unsaponifiable fat.\",\"PeriodicalId\":19944,\"journal\":{\"name\":\"Pharmacy Education\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2024-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmacy Education\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46542/pe.2024.242.3238\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"EDUCATION, SCIENTIFIC DISCIPLINES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacy Education","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46542/pe.2024.242.3238","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"EDUCATION, SCIENTIFIC DISCIPLINES","Score":null,"Total":0}
Formulation and effectiveness of solid soap preparations from citronella grass (Cymbopogon nardus L.) essential oil extract against Listeria monocytogenes
Background: The components of essential oils, such as citronellol, citronellal, and geraniol have been reported to possess the ability to inhibit bacteria. Furthermore, Listeria monocytogenes is a bacteria that often affects humans and its infections can cause meningitis and bacteremia. In pregnant women, Listeria monocytogenes can cause flu-like syndrome with complications of miscarriage, infant death, and meningitis in infants.
Objective: This study evaluated the suitability of solid soap preparations from Citronella grass essential oil, based on its physical properties, such as organoleptic tests, as well as assessments of chemical tests and the effectiveness of the sample produced against bacteria.
Method: The soap-making process was initiated by mixing the fat fraction (stearic acid and coconut oil) with an alkali, namely 30% NaOH. The soap stock was then added to the other ingredients and stirred until it became homogeneous for testing.
Results: The test showed a pH value, water content, total fat, ethanol insoluble material, free fatty acids, chloride content, and unsaponificable fat of 10.8, 14.26, 74.84, 2.4, 0.26, 0.48, and 85.8, respectively. Furthermore, the sample showed a high level of inhibition against Listeria monocytogenes.
Conclusion: Evaluation of citronella essential oil extract soap met the requirements, except for its unsaponifiable fat.
期刊介绍:
Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.