自适应两阶段设计的最佳条件误差函数新结果

IF 1.2 4区数学 Q2 STATISTICS & PROBABILITY

Journal of Applied Statistics Pub Date : 2024-04-17 DOI:10.1080/02664763.2024.2342424

Maximilian Pilz, Meinhard Kieser

引用次数: 0

摘要

采用适应性设计的临床试验中的非盲法中期分析越来越受欢迎。在这里，通过定义适当的条件误差函数来控制 I 型误差率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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New results on optimal conditional error functions for adaptive two-stage designs

Unblinded interim analyses in clinical trials with adaptive designs are gaining increasing popularity. Here, the type I error rate is controlled by defining an appropriate conditional error functio...

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来源期刊

Journal of Applied Statistics 数学-统计学与概率论

CiteScore

3.40

自引率

0.00%

发文量

126

审稿时长

6 months

期刊介绍： Journal of Applied Statistics provides a forum for communication between both applied statisticians and users of applied statistical techniques across a wide range of disciplines. These areas include business, computing, economics, ecology, education, management, medicine, operational research and sociology, but papers from other areas are also considered. The editorial policy is to publish rigorous but clear and accessible papers on applied techniques. Purely theoretical papers are avoided but those on theoretical developments which clearly demonstrate significant applied potential are welcomed. Each paper is submitted to at least two independent referees.