发育中上丘的超多重性和不可预测性

IF 14.6 1区医学 Q1 NEUROSCIENCES

Trends in Neurosciences Pub Date : 2024-04-01 Epub Date: 2024-03-20 DOI:10.1016/j.tins.2024.03.001

Andrii Rudenko, In-Jung Kim

引用次数: 0

摘要

Cheung、Pauler、Koppensteiner 等人最近的一项研究将系追踪与单细胞 RNA 测序（scRNA-seq）相结合，揭示了发育中的上丘脑（SC）的意外特征。极具多能性的单个祖细胞产生了所有类型的上丘脑神经元和胶质细胞，这些细胞以一种非预定的模式定位，显示了上丘脑发育过程中显著的不可预测性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Supermultipotency and unpredictability in the developing superior colliculus.

A recent study by Cheung, Pauler, Koppensteiner et al. combining lineage tracing with single-cell RNA sequencing (scRNA-seq) has revealed unexpected features of the developing superior colliculus (SC). Extremely multipotent individual progenitors generate all types of SC neurons and glial cells that were found to localize in a non-predetermined pattern, demonstrating a remarkable degree of unpredictability in SC development.

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来源期刊

Trends in Neurosciences 医学-神经科学

CiteScore

26.50

自引率

1.30%

发文量

123

审稿时长

6-12 weeks

期刊介绍： For over four decades, Trends in Neurosciences (TINS) has been a prominent source of inspiring reviews and commentaries across all disciplines of neuroscience. TINS is a monthly, peer-reviewed journal, and its articles are curated by the Editor and authored by leading researchers in their respective fields. The journal communicates exciting advances in brain research, serves as a voice for the global neuroscience community, and highlights the contribution of neuroscientific research to medicine and society.