严重术前残疾与退行性脊椎滑脱症手术后心理健康改善程度相关:队列匹配分析

IF 3.8 2区 医学 Q1 CLINICAL NEUROLOGY
Neurospine Pub Date : 2024-03-01 Epub Date: 2024-01-31 DOI:10.14245/ns.2347080.540
Ishan Khosla, Fatima N Anwar, Andrea M Roca, Srinath S Medakkar, Alexandra C Loya, Aayush Kaul, Jacob C Wolf, Vincent P Federico, Arash J Sayari, Gregory D Lopez, Kern Singh
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引用次数: 0

摘要

目的评估退行性脊柱滑脱症(DS)手术后术前残疾对患者报告结果(PROs)的影响:方法:从单一外科医生脊柱登记处回顾性地识别出接受手术治疗的脊柱退行性关节炎患者。根据奥斯韦特里残疾指数(ODI)进行分组:共纳入 214 名患者,其中轻度残疾组有 77 人。重度残疾组术后第1天疼痛评分更差,住院时间更长(两组P均≤0.038)。重度残疾组的术前和术后效果更差(P结论:与残疾程度较轻的患者相比,基线残疾程度较重的患者报告的 POD 1 疼痛程度较高,出院时间较晚。虽然这些患者在术前和术后的身体/精神健康状况较差,但他们在术后的精神健康和残疾状况却有较大改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Severe Preoperative Disability Is Associated With Greater Mental Health Improvements Following Surgery for Degenerative Spondylolisthesis: A Cohort Matched Analysis.

Objective: To evaluate preoperative disability's influence on patient-reported outcomes (PROs) following surgery for degenerative spondylolisthesis (DS).

Methods: DS patients who underwent surgical intervention were retrospectively identified from a single-surgeon spine registry. Cohorts based on Oswestry Disability Index (ODI) < 41 (milder disability) and ≥ 41 (severe disability) were created. Demographic differences were accounted for with 1:1 propensity score matching. For the matched sample, perioperative and PRO data were additionally collected. PROs assessed included mental health, physical function, pain, and disability. Pre- and up to 2-year postoperative PROs were utilized. Average time to final follow-up was 15.7 ± 8.8 months. Improvements in PROs and minimal clinically important difference (MCID) rates were calculated. Continuous variables were compared through Student t-test and categorical variables were compared through chi-square tests.

Results: Altogether, 214 patients were included with 77 in the milder disability group. The severe disability group had worse postoperative day (POD) 1 pain scores and longer hospital stays (p ≤ 0.038, both). The severe disability group reported worse outcomes pre- and postoperatively (p < 0.011, all), but had greater average improvement in 12-item Short Form health survey mental composite score (SF-12 MCS), 9-Item Patient Health Questionnaire (PHQ-9), visual analogue scale (VAS)-back, and ODI by 6 weeks (p ≤ 0.037, all) and PHQ-9, VAS-back and ODI by final follow-up (p ≤ 0.015, all). The severe disability cohort was more likely to achieve MCID for SF-12 MCS, PHQ-9, and ODI (p ≤ 0.003, all).

Conclusion: Patients with greater baseline disability report higher POD 1 pain and discharge later than patients with milder disability. While these patients report inferior physical/mental health before and after surgery, they report greater improvements in mental health and disability postoperatively.

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来源期刊
Neurospine
Neurospine Multiple-
CiteScore
5.80
自引率
18.80%
发文量
93
审稿时长
10 weeks
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