这根大麻烟里有多少四氢大麻酚?对年轻人了解大麻产品中大麻素含量情况的日常日记研究。

IF 2.4 3区 医学 Q2 PSYCHOLOGY
Journal of studies on alcohol and drugs Pub Date : 2024-07-01 Epub Date: 2024-02-06 DOI:10.15288/jsad.23-00228
Sophie G Coelho, Christian S Hendershot, Nicolle Fox, Jeffrey D Wardell
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引用次数: 0

摘要

目的:许多年轻成年人表示经常使用大麻,并面临大麻危害的风险。了解大麻产品中四氢大麻酚(THC)和大麻二酚(CBD)的浓度可能有助于减少危害,但很少有研究对这一人群的大麻素浓度知识进行描述。本研究使用日级数据来研究大麻素浓度知识的预测因素,以及大麻素浓度知识与年轻成年人中药物相关后果的关联:一项关于大麻和酒精共同使用的大型研究的参与者(人数=131;平均年龄 22.11 岁,64.12% 为女性)在 21 天内完成了每日调查,评估对所使用大麻的大麻素浓度、所使用大麻的形式、使用大麻的动机(药用、非药用、两者兼有)以及与药物相关的后果的了解程度:平均而言,在 48% 和 32% 的吸食大麻天数中,参与者至少对大麻中四氢大麻酚和大麻二酚的浓度有所了解。广义线性混合模型显示,在控制社会人口因素和大麻参与程度的情况下,更倾向于使用非鲜花(相对于鲜花)大麻产品和报告有药用(相对于纯粹非药用)大麻使用动机的参与者在各天报告的大麻素浓度知识总体上更多。总体大麻素浓度知识较多的参与者更经常报告与药物有关的积极后果。此外,在大麻素浓度已知与未知的日子里,参与者更有可能报告与药物有关的负面后果:研究结果表明,在报告主要使用非鲜花大麻和药用大麻的年轻成年人中,大麻素浓度知识可能较高,但仅凭大麻素浓度知识可能并不能在一天的水平上防止与药物有关的负面后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
How Much THC Is in That Joint? A Daily Diary Study of Young Adults' Knowledge of the Cannabinoid Content of Cannabis Products.

Objective: Many young adults report frequent cannabis use and are at risk for cannabis harms. Knowledge of the tetrahydrocannabinol (THC) and cannabidiol (CBD) concentrations of cannabis products may promote harm reduction, but few studies have characterized cannabinoid concentration knowledge in this population. This study used day-level data to examine predictors of cannabinoid concentration knowledge and associations of cannabinoid concentration knowledge with substance-related consequences among young adults.

Method: Participants (n = 131; mean age = 22.11 years; 64.12% female) from a larger study of cannabis and alcohol co-use completed daily surveys over 21 days assessing knowledge of the cannabinoid concentrations of cannabis used, forms of cannabis used, motives for cannabis use (medicinal, nonmedicinal, both), and substance-related consequences.

Results: On average, participants reported at least some knowledge of the THC and CBD concentrations of their cannabis on 48% and 32% of their cannabis use days, respectively. Generalized linear mixed models revealed that participants with a greater propensity to use nonflower (relative to flower) cannabis products and to report medicinal (relative to exclusively nonmedicinal) motives for cannabis use reported greater cannabinoid concentration knowledge overall across days, controlling for sociodemographic factors and level of cannabis involvement. Participants with greater overall cannabinoid concentration knowledge reported positive substance-related consequences more often. In addition, participants were more likely to report negative substance-related consequences on days during which cannabinoid concentrations were known versus unknown.

Conclusions: Findings suggest that cannabinoid concentration knowledge may be higher among young adults who report primarily nonflower and medicinally motivated cannabis use, although cannabinoid concentration knowledge, alone, may not protect against negative substance-related consequences at the day level.

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来源期刊
CiteScore
4.80
自引率
5.90%
发文量
224
审稿时长
3 months
期刊介绍: The Journal of Studies on Alcohol and Drugs began in 1940 as the Quarterly Journal of Studies on Alcohol. It was founded by Howard W. Haggard, M.D., director of Yale University’s Laboratory of Applied Physiology. Dr. Haggard was a physiologist studying the effects of alcohol on the body, and he started the Journal as a way to publish the increasing amount of research on alcohol use, abuse, and treatment that emerged from Yale and other institutions in the years following the repeal of Prohibition in 1933. In addition to original research, the Journal also published abstracts summarizing other published documents dealing with alcohol. At Yale, Dr. Haggard built a large team of alcohol researchers within the Laboratory of Applied Physiology—including E.M. Jellinek, who became managing editor of the Journal in 1941. In 1943, to bring together the various alcohol research projects conducted by the Laboratory, Dr. Haggard formed the Section of Studies on Alcohol, which also became home to the Journal and its editorial staff. In 1950, the Section was renamed the Center of Alcohol Studies.
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