Yunhua Chen , Muyuan Chai , Chengkai Xuan , Jiayi Lin , Huishang Yang , Chunhui Li , Manshan Xie , Serge Ostrovidov , Xuetao Shi , Chuanbin Mao
{"title":"调整外科聚合物材料的特性,改善软组织伤口的闭合和愈合","authors":"Yunhua Chen , Muyuan Chai , Chengkai Xuan , Jiayi Lin , Huishang Yang , Chunhui Li , Manshan Xie , Serge Ostrovidov , Xuetao Shi , Chuanbin Mao","doi":"10.1016/j.pmatsci.2024.101249","DOIUrl":null,"url":null,"abstract":"<div><p>Effective wound management is important, as millions of people suffer traumatic injuries and surgical operations annually. Proper wound closure is essential for the structural and functional restoration of damaged tissues. In addition to conventional sutures, various advanced surgical materials with multiple functions have been developed for more reliable and improved wound healing performance in the past few years. Here, polymeric surgical materials for soft tissue wound closure are comprehensively reviewed, including both commercially available materials and newly developed materials. These materials, based on natural, synthetic or composite polymers, are classified and discussed as invasive and non-invasive surgical materials. Their properties (antibacterial, hemostatic, stimuli-responsive, drug delivery, or a combination thereof) are critically analysed in the context of improving wound healing. Moreover, how to tune these properties (e.g., chemical grafting of antibacterial moieties, nano-enabled regulation of hemostasis, dual stimuli-responsive design, etc.) are clearly discussed. Finally, challenges in the field and potential solutions to tackle them are also proposed. This review should inspire more research efforts to develop the next generation of promising surgical polymeric materials for clinical applications.</p></div>","PeriodicalId":411,"journal":{"name":"Progress in Materials Science","volume":null,"pages":null},"PeriodicalIF":33.6000,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Tuning the properties of surgical polymeric materials for improved soft-tissue wound closure and healing\",\"authors\":\"Yunhua Chen , Muyuan Chai , Chengkai Xuan , Jiayi Lin , Huishang Yang , Chunhui Li , Manshan Xie , Serge Ostrovidov , Xuetao Shi , Chuanbin Mao\",\"doi\":\"10.1016/j.pmatsci.2024.101249\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Effective wound management is important, as millions of people suffer traumatic injuries and surgical operations annually. Proper wound closure is essential for the structural and functional restoration of damaged tissues. In addition to conventional sutures, various advanced surgical materials with multiple functions have been developed for more reliable and improved wound healing performance in the past few years. Here, polymeric surgical materials for soft tissue wound closure are comprehensively reviewed, including both commercially available materials and newly developed materials. These materials, based on natural, synthetic or composite polymers, are classified and discussed as invasive and non-invasive surgical materials. Their properties (antibacterial, hemostatic, stimuli-responsive, drug delivery, or a combination thereof) are critically analysed in the context of improving wound healing. Moreover, how to tune these properties (e.g., chemical grafting of antibacterial moieties, nano-enabled regulation of hemostasis, dual stimuli-responsive design, etc.) are clearly discussed. Finally, challenges in the field and potential solutions to tackle them are also proposed. This review should inspire more research efforts to develop the next generation of promising surgical polymeric materials for clinical applications.</p></div>\",\"PeriodicalId\":411,\"journal\":{\"name\":\"Progress in Materials Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":33.6000,\"publicationDate\":\"2024-02-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Progress in Materials Science\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0079642524000185\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in Materials Science","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0079642524000185","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Tuning the properties of surgical polymeric materials for improved soft-tissue wound closure and healing
Effective wound management is important, as millions of people suffer traumatic injuries and surgical operations annually. Proper wound closure is essential for the structural and functional restoration of damaged tissues. In addition to conventional sutures, various advanced surgical materials with multiple functions have been developed for more reliable and improved wound healing performance in the past few years. Here, polymeric surgical materials for soft tissue wound closure are comprehensively reviewed, including both commercially available materials and newly developed materials. These materials, based on natural, synthetic or composite polymers, are classified and discussed as invasive and non-invasive surgical materials. Their properties (antibacterial, hemostatic, stimuli-responsive, drug delivery, or a combination thereof) are critically analysed in the context of improving wound healing. Moreover, how to tune these properties (e.g., chemical grafting of antibacterial moieties, nano-enabled regulation of hemostasis, dual stimuli-responsive design, etc.) are clearly discussed. Finally, challenges in the field and potential solutions to tackle them are also proposed. This review should inspire more research efforts to develop the next generation of promising surgical polymeric materials for clinical applications.
期刊介绍:
Progress in Materials Science is a journal that publishes authoritative and critical reviews of recent advances in the science of materials. The focus of the journal is on the fundamental aspects of materials science, particularly those concerning microstructure and nanostructure and their relationship to properties. Emphasis is also placed on the thermodynamics, kinetics, mechanisms, and modeling of processes within materials, as well as the understanding of material properties in engineering and other applications.
The journal welcomes reviews from authors who are active leaders in the field of materials science and have a strong scientific track record. Materials of interest include metallic, ceramic, polymeric, biological, medical, and composite materials in all forms.
Manuscripts submitted to Progress in Materials Science are generally longer than those found in other research journals. While the focus is on invited reviews, interested authors may submit a proposal for consideration. Non-invited manuscripts are required to be preceded by the submission of a proposal. Authors publishing in Progress in Materials Science have the option to publish their research via subscription or open access. Open access publication requires the author or research funder to meet a publication fee (APC).
Abstracting and indexing services for Progress in Materials Science include Current Contents, Science Citation Index Expanded, Materials Science Citation Index, Chemical Abstracts, Engineering Index, INSPEC, and Scopus.