一名患有温切斯特综合征的儿童对口服倍他米松和甲氨蝶呤有反应。

IF 1.2 4区医学 Q3 DERMATOLOGY

Pediatric Dermatology Pub Date : 2024-07-01 Epub Date: 2024-01-30 DOI:10.1111/pde.15543

Gaurav Dash, Swetalina Pradhan, Upasna Sinha, Ruchi Sinha

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引用次数: 0

摘要

温彻斯特综合征（WS）是一种罕见的遗传性疾病，迄今为止仅有少数病例报道。我们报告了一名 14 岁男性患者的病例，他出现生长迟缓、左下肢因皮肤厚而挛缩、多毛症和双侧角膜混浊。在口服倍他米松脉冲和每周口服甲氨蝶呤后，关节挛缩得到了完全改善。

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A child with Winchester syndrome responding to oral betamethasone and methotrexate.

Winchester syndrome (WS) is a rare genetic disorder with a handful of cases reported to date. We report a 14-year-old male who presented with growth retardation, contracture of left lower limb due to thick indurated skin, hypertrichosis, and bilateral corneal opacity. There was complete improvement in joint contracture with oral betamethasone pulse and weekly oral methotrexate.

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来源期刊

Pediatric Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

6.70%

发文量

269

审稿时长

1 months

期刊介绍： Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.