体育锻炼和纤维摄入有利于在衰老过程中保持肌肉质量和力量:英国生物库队列综合横断面研究

Jordi Morwani-Mangnani, Mar Rodriguez-Girondo, Cecile Singh-Povel, Sjors Verlaan, Marian Beekman, P. Eline Slagboom
{"title":"体育锻炼和纤维摄入有利于在衰老过程中保持肌肉质量和力量:英国生物库队列综合横断面研究","authors":"Jordi Morwani-Mangnani, Mar Rodriguez-Girondo, Cecile Singh-Povel, Sjors Verlaan, Marian Beekman, P. Eline Slagboom","doi":"10.1101/2024.01.22.23300657","DOIUrl":null,"url":null,"abstract":"Background: Aging triggers intricate physiological changes, particularly in muscle mass and strength, affecting overall health and independence. Despite existing research, the broader significance of how muscle health is affected by the intricate interplay of lifestyle factors simultaneously during aging needs more exploration. This study aims to examine how nutrition, exercise, and sleep independently and differentially impact on muscle mass and strength in middle-aged men and women, facilitating future personalized recommendations for preserving muscle health.\nMethods: The cross-sectional analysis of the UK Biobank involved 45,984 individuals aged 40-70. Multiple linear regression explored determinants of whole-body fat-free mass and handgrip strength, considering traditional, socio-demographics, medication use and smoking as covariates, with gender and age (younger and older than 55 years) stratifications.\nResults: Higher physical activity and fiber intake beneficially affect both muscle mass and strength, especially above 55 years. Other lifestyle factors influence the two muscle parameters differently. Key determinants influencing muscle strength included higher protein intake, lower water intake, higher alcohol intake, and extended sleep duration whereas mainly higher water intake contributes to higher muscle mass. Interpretation: Physical activity and fiber intake associate with increased muscle strength and mass which may connect gut and muscle health. Given the observed complexity of muscle health in the age and gender strata, further longitudinal research is needed to provide personalized lifestyle recommendations.","PeriodicalId":501025,"journal":{"name":"medRxiv - Geriatric Medicine","volume":"242 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Physical activity and fiber intake beneficial for muscle mass and strength preservation during aging: A Comprehensive Cross-Sectional Study in the UK Biobank cohort\",\"authors\":\"Jordi Morwani-Mangnani, Mar Rodriguez-Girondo, Cecile Singh-Povel, Sjors Verlaan, Marian Beekman, P. Eline Slagboom\",\"doi\":\"10.1101/2024.01.22.23300657\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Aging triggers intricate physiological changes, particularly in muscle mass and strength, affecting overall health and independence. Despite existing research, the broader significance of how muscle health is affected by the intricate interplay of lifestyle factors simultaneously during aging needs more exploration. This study aims to examine how nutrition, exercise, and sleep independently and differentially impact on muscle mass and strength in middle-aged men and women, facilitating future personalized recommendations for preserving muscle health.\\nMethods: The cross-sectional analysis of the UK Biobank involved 45,984 individuals aged 40-70. Multiple linear regression explored determinants of whole-body fat-free mass and handgrip strength, considering traditional, socio-demographics, medication use and smoking as covariates, with gender and age (younger and older than 55 years) stratifications.\\nResults: Higher physical activity and fiber intake beneficially affect both muscle mass and strength, especially above 55 years. Other lifestyle factors influence the two muscle parameters differently. Key determinants influencing muscle strength included higher protein intake, lower water intake, higher alcohol intake, and extended sleep duration whereas mainly higher water intake contributes to higher muscle mass. Interpretation: Physical activity and fiber intake associate with increased muscle strength and mass which may connect gut and muscle health. Given the observed complexity of muscle health in the age and gender strata, further longitudinal research is needed to provide personalized lifestyle recommendations.\",\"PeriodicalId\":501025,\"journal\":{\"name\":\"medRxiv - Geriatric Medicine\",\"volume\":\"242 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Geriatric Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.01.22.23300657\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Geriatric Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.01.22.23300657","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景:衰老会引发复杂的生理变化,尤其是肌肉质量和力量的变化,从而影响整体健康和独立性。尽管已有研究,但在衰老过程中,各种生活方式因素同时发生的错综复杂的相互作用如何影响肌肉健康,这一更广泛的意义还需要更多的探索。本研究旨在探讨营养、运动和睡眠如何对中年男性和女性的肌肉质量和力量产生独立且不同的影响,从而为未来保护肌肉健康提供个性化建议:英国生物库的横断面分析涉及 45,984 名 40-70 岁的人。多元线性回归探讨了全身去脂质量和握力的决定因素,考虑了传统、社会人口、药物使用和吸烟等协变量,并对性别和年龄(55 岁以下和 55 岁以上)进行了分层:结果:更多的体育锻炼和纤维摄入对肌肉质量和力量都有好处,尤其是 55 岁以上人群。其他生活方式因素对这两项肌肉参数的影响各不相同。影响肌肉力量的主要决定因素包括蛋白质摄入量较高、水摄入量较低、酒精摄入量较高和睡眠时间延长,而水摄入量较高主要有助于提高肌肉质量。解释:体力活动和纤维摄入量与肌肉强度和质量的增加有关,这可能会将肠道和肌肉健康联系起来。鉴于所观察到的不同年龄和性别阶层肌肉健康的复杂性,需要进一步开展纵向研究,以提供个性化的生活方式建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Physical activity and fiber intake beneficial for muscle mass and strength preservation during aging: A Comprehensive Cross-Sectional Study in the UK Biobank cohort
Background: Aging triggers intricate physiological changes, particularly in muscle mass and strength, affecting overall health and independence. Despite existing research, the broader significance of how muscle health is affected by the intricate interplay of lifestyle factors simultaneously during aging needs more exploration. This study aims to examine how nutrition, exercise, and sleep independently and differentially impact on muscle mass and strength in middle-aged men and women, facilitating future personalized recommendations for preserving muscle health. Methods: The cross-sectional analysis of the UK Biobank involved 45,984 individuals aged 40-70. Multiple linear regression explored determinants of whole-body fat-free mass and handgrip strength, considering traditional, socio-demographics, medication use and smoking as covariates, with gender and age (younger and older than 55 years) stratifications. Results: Higher physical activity and fiber intake beneficially affect both muscle mass and strength, especially above 55 years. Other lifestyle factors influence the two muscle parameters differently. Key determinants influencing muscle strength included higher protein intake, lower water intake, higher alcohol intake, and extended sleep duration whereas mainly higher water intake contributes to higher muscle mass. Interpretation: Physical activity and fiber intake associate with increased muscle strength and mass which may connect gut and muscle health. Given the observed complexity of muscle health in the age and gender strata, further longitudinal research is needed to provide personalized lifestyle recommendations.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信