medRxiv - Geriatric Medicine

Daily consumption of ketone ester, bis octanoyl (R)-1,3-butanediol does not impact functional and quality of life outcomes in healthy older adults, a randomized, parallel arm, double-blind, placebo-controlled study

Pub Date : 2024-09-18 DOI: 10.1101/2024.09.17.24313811 Brianna J Stubbs, Elizabeth B Stephens, Chatura Senaheera, Sawyer Peralta, Stephanie Roa Diaz, Laura Alexander, Wendie Silverman Martin, Jamie Kurtzig, Thelma Y Garcia, Michi Yukawa, Jennifer Morris, Traci M Blonquist, James B Johnson, John C Newman

Longitudinal changes in epigenetic clocks predict survival in the InCHIANTI cohort

Pub Date : 2024-09-15 DOI: 10.1101/2024.09.13.24313620 Pei-Lun Kuo, Ann Zenobia Moore, Toshiko Tanaka, Daniel W. Belsky, Ake Tzu-Hui Lu, Steve Horvath, Stefania Bandinelli, Luigi Ferrucci

Safety and efficacy of rapamycin on healthspan metrics after one year: PEARL Trial Results

Pub Date : 2024-08-26 DOI: 10.1101/2024.08.21.24312372 Girish Harinath, Virginia Lee, Andy Nyquist, Mauricio Moel, Jesper Hagemeier, Stefanie L Morgan, Anar Isman, Sajad Zalzala