乳清蛋白复合物与低强度运动相结合对慢性阻塞性肺病稳定期老年住院患者的影响。

IF 1.3 4区 医学 Q4 NUTRITION & DIETETICS
Min Zong, Honghua Shen, Lei Ren, Tao Han, Jie Chen, Yanqiu Chen, Jiashuo Lu, Yin Zhang, Shijie Li, Jianqin Sun
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引用次数: 0

摘要

背景和目的:以往的文献大多证明了肺康复(PR)与全营养粉相结合对慢性阻塞性肺病(COPD)患者的疗效。然而,乳清蛋白作为口服营养补充剂(ONS)在肺康复期间的益处尚不明确:试验历时12周,我们将90名稳定期慢性阻塞性肺病老年患者随机分为低强度运动组(30人,PR组)、PR加复合乳清蛋白组(30人,PRWP组)和对照组(30人),并评估运动能力、精神健康状况、肺功能和身体成分等指标。最终,84人坚持到试验结束:与对照组相比,PRWP 组和 PR 组的手握力(HGS)(分别为 1.4 ± 0.6 kg 和 1.0 ± 0.2 kg,P< 0.05)、6 分钟步行距离(6MWD)(14.1 ± 3.8 米,P< 0.05)均有所改善。此外,与 PR 组相比,PRWP 组的医学研究委员会呼吸困难量表(MRC)(-0.2 ± 0.1,p< 0.01)、焦虑评分(-1.2 ± 0.4,p< 0.01)和体重(2.0 ± 0.8kg,p< 0.05)均有所改善。无脂肪质量指数和骨骼肌质量指数没有组间差异:结论:两种干预模式都能增强肌肉力量。结论:两种干预模式都能增强肌肉力量,添加复合乳清蛋白还能成功纠正运动引起的呼吸困难、焦虑和体重减轻。这种康复模式可能对老年慢性阻塞性肺病患者很有价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of whey protein complex combined with low-intensity exercise in elderly inpatients with COPD at a stable stage.

Background and objectives: Previous literature mostly has demonstrated the efficacy of pulmonary rehabilitation (PR) combined with whole nutrition powder in patients with chronic obstructive pulmonary disease (COPD). However, the benefits of whey protein as an oral nutritional supplement (ONS) during PR are not clear.

Methods and study design: It took 12 weeks to complete the trial, we divided 90 elderly patients with stable-stage COPD into a low-intensity exercise group (n= 30, PR group), PR plus whey proteins complex group (n= 30, PRWP group), and a control group (n= 30) randomly, and assessed index such as exercise capacity, mental health status, lung function, and body composition. Eventually, 84 people persisted until the end of the trial.

Results: Compared with the control group, hand grip strength (HGS)(1.4 ± 0.6 kg, and 1.0 ± 0.2 kg respectively, p< 0.05) in the PRWP and PR group, 6 minutes of walking distance (6MWD)(14.1 ± 3.8m, p< 0.05) in PRWP group improved. Furthermore, compared with the PR group, Medical Research Council Dyspnea Scale (MRC)(-0.2 ± 0.1, p< 0.01), anxiety score (-1.2 ± 0.4, p< 0.01), and body weight (2.0 ± 0.8kg, p< 0.05) improved in the PRWP group. There were no inter-group differences in a fat-free mass index or appendicular skeletal muscle mass index.

Conclusions: Muscle strength could be enhanced in both intervention models. Adding whey protein complex was additionally successful in rectifying dyspnea, anxiety, and weight loss caused by exercise. This rehabilitation pattern might be valuable in elderly patients with COPD.

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来源期刊
CiteScore
2.50
自引率
7.70%
发文量
58
审稿时长
6-12 weeks
期刊介绍: The aims of the Asia Pacific Journal of Clinical Nutrition (APJCN) are to publish high quality clinical nutrition relevant research findings which can build the capacity of clinical nutritionists in the region and enhance the practice of human nutrition and related disciplines for health promotion and disease prevention. APJCN will publish original research reports, reviews, short communications and case reports. News, book reviews and other items will also be included. The acceptance criteria for all papers are the quality and originality of the research and its significance to our readership. Except where otherwise stated, manuscripts are peer-reviewed by at least two anonymous reviewers and the Editor. The Editorial Board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as material cannot be returned. Final acceptance or rejection rests with the Editorial Board
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