重症创伤患者的急性肌肉萎缩率评估和长期死亡率。

IF 1.3 4区 医学 Q4 NUTRITION & DIETETICS
Yong You, Shuyun Wu, Xiaofang Guo, Ming Chen, Yan Wang, Wenkui Yu
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引用次数: 0

摘要

背景和目的:评估重症创伤患者急性肌肉萎缩率与长期死亡率之间的关系:评估重症创伤患者急性肌肉萎缩率与长期死亡率之间的关系:对重症创伤患者进行单中心回顾性研究。研究招募了在创伤后 24 小时内和 1 周内接受计算机断层扫描(包括 L3 椎体)的患者。急性肌肉萎缩率定义为创伤后一周内骨骼肌指数每天变化的平均百分比。研究人员进行了多变量逻辑回归分析和接收器操作特征曲线分析,以确定急性肌肉萎缩率是否有助于预测住院营养不良和1年死亡率:结果:骨骼肌指数在基线时为 49.3±10.7 cm2/m2,随后下降至 45.1±9.6 cm2/m2(p结论:急性肌肉萎缩率是预测住院营养不良和 1 年死亡率的独立指标:急性肌肉萎缩率与重症创伤患者较高的1年死亡率和住院营养不良率密切相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acute muscle wasting rate assessment and long-term mortality in critically ill trauma.

Background and objectives: To evaluate the relationship between acute muscle wasting rate and long-term mortality in critically ill trauma.

Methods and study design: A single-center, retrospective study was conducted in critically ill trauma. Patients with Computed Tomography scans including the L3 vertebra within 24 hours and at 1 week after trauma were recruited. Acute muscle wasting rate was defined as the mean percent variation per day of skeletal muscle index in the first week after trauma. Multivariate logistic regression analysis and receiver operating characteristic curve analysis were performed to determine whether acute muscle wasting rate could help predict hospital malnutrition and 1-year mortality.

Results: Skeletal muscle index was 49.3±10.7 cm2/m2 at baseline and decreased to 45.1±9.6 cm2/m2 (p<0.001) at 1 week and 39.8±10.8cm2/m2 (p<0.001) at 1 month after trauma. A sustained decrease of skeletal muscle index was observed from baseline up to 6 months (33.7±8.4cm2/m2, p<0.001) post trauma, and lasted for 1 year (37.7±5.6cm2/m2, p=0.004). Logistic regression analysis showed that acute muscle wasting rate was an independent risk factor for hospital malnutrition and 1-year mortality. Every 1% absolute increase of acute muscle wasting rate was associated with 1.82-fold higher odds of 1-year mortality in critically ill trauma. The area under curve of acute muscle wasting rate was 0.813 for hospital malnutrition prediction and 0.715 for 1-year mortality prediction.

Conclusions: Acute muscle wasting rate was independently associated with higher 1-year mortality and hospital malnutrition in critically ill trauma.

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来源期刊
CiteScore
2.50
自引率
7.70%
发文量
58
审稿时长
6-12 weeks
期刊介绍: The aims of the Asia Pacific Journal of Clinical Nutrition (APJCN) are to publish high quality clinical nutrition relevant research findings which can build the capacity of clinical nutritionists in the region and enhance the practice of human nutrition and related disciplines for health promotion and disease prevention. APJCN will publish original research reports, reviews, short communications and case reports. News, book reviews and other items will also be included. The acceptance criteria for all papers are the quality and originality of the research and its significance to our readership. Except where otherwise stated, manuscripts are peer-reviewed by at least two anonymous reviewers and the Editor. The Editorial Board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as material cannot be returned. Final acceptance or rejection rests with the Editorial Board
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