血、尿睾酮对多囊卵巢综合征诊断的观察分析

IF 0.5 Q4 EDUCATION, SCIENTIFIC DISCIPLINES

Pharmacy Education Pub Date : 2023-10-10 DOI:10.46542/pe.2023.234.259263

M.A. Hanny Ferry Fernanda, None Ashon Sa’adi, None Sudjarwo

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引用次数: 0

摘要

背景:女性多囊卵巢综合征(PCOS)诊断的重要工具是血睾酮水平升高。尿液中睾酮的存在很可能支持多囊卵巢综合征的诊断;然而，需要更多的研究来确定血液睾酮水平是否与多囊卵巢综合征有关。目的:采用诊断试验方法对30例pcos阳性妇女进行观察性研究。方法:采用酶联免疫吸附法(ELISA)测定妇女尿液和血清中睾酮的含量。结果:30例PCOS患者尿睾酮水平低于血清睾酮水平，分别为2.688 nmol/L和8.067 nmol/L。Spearman相关检验结果为0.39，显著性水平为0.05，截断值为2.6010 nmol/L，敏感性为0.625，特异性为0.571，说明尿睾酮水平对检测高雄激素性PCOS患者的重要性。结论:PCOS患者血清与尿睾酮水平存在相关性。

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An observational analysis of blood and urine testosterone in diagnosis of polycystic ovarian syndrome

Background: An important diagnostic tool for the diagnosis of Polycystic ovarian syndrome (PCOS) in women is elevated blood testosterone levels. The presence of testosterone in the urine is very likely to support the PCOS diagnosis; however, more investigation is required to determine whether blood testosterone levels are associated with PCOS. Objective: A total of 30 PCOS-positive women participated in this observational study using a diagnostic test approach. Method: The ELISA technique was used to measure the amounts of testosterone in the woman's urine and serum. Result: The levels of testosterone in the urine of 30 PCOS women were lower than those in the serum, with values of 2.688 nmol/L and 8.067 nmol/L, respectively. The Spearman correlation test findings revealed a value of 0.39 at a significance level of 0.05, with a cut-off value of 2.6010 nmol/L at sensitivity and specificity of 0.625 and 0.571, showing the importance of urine testosterone levels in detecting hyperandrogenic PCOS patients. Conclusion: In women with PCOS, serum and urine testosterone levels are correlated.

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来源期刊

Pharmacy Education EDUCATION, SCIENTIFIC DISCIPLINES-

CiteScore

0.80

自引率

20.00%

发文量

174

期刊介绍： Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.