用于开发生物传感器的标准硅CMOS器件

2006 13th International Symposium on the Physical and Failure Analysis of Integrated Circuits Pub Date : 2006-07-03 DOI:10.1109/IPFA.2006.251047

E. Volynsky, E. Frenkel-Ben-Yakar, Y. Sternberg

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引用次数: 0

摘要

D. Diamond(1998)提出的抗体/抗原概念生物传感器由于其对特定生物分子的高选择性，在过去十年中取得了令人印象深刻的发展。它们可以快速和早期发现各种疾病和感染。该领域的主要挑战之一是开发可以轻松插入人体内的生物传感器，并通过对抗体浓度的变化做出反应来充当“疾病或身体功能障碍探测器”。研究人员在这方面面临的一个重要问题是，如K. Gartsman等人(1998)所述，通过使用D. G. Wu等人(2000)中提出的已知且廉价的技术来构建生物传感器。硅(Si)的使用在这个意义上是非常有吸引力的，因为它的低价格和高可靠性

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Standard Silicon CMOS Device uses for developing a Biological Sensor

Antibody/antigen concept biological sensors as presented in D. Diamond (1998) have shown a very impressive growth in the last decade due to their high selectivity to specific biomolecules. They can allow fast and early detection of various kinds of illnesses and infections. One of the main challenges in this field is to develop biosensors that can be easily inserted within the human body and act as "illness or body malfunction detectors" by reacting to changes in antibody concentration. An important issue facing researchers in this aspect is to build biosensors as stated in K. Gartsman et al. (1998) by using known and inexpensive technologies presented in D. G. Wu et al. (2000). The use of silicon (Si) is very attractive in this sense due to its low price and high reliability

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2006 13th International Symposium on the Physical and Failure Analysis of Integrated Circuits

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