利用单轴排列的心肌细胞收集能量

Xia Liu, X. Wang, Song Li, Liwei Lin
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引用次数: 2

摘要

本文首次提出了在柔性基质上从单轴排列的心肌细胞(CMs)收集能量的概念。实验发现,在0.5Hz同步收缩新生大鼠心室心肌细胞(NRVCMs)时,压电能量采集器的机械应变分别产生87.5nA和92.3mV的峰值电流和电压。这项工作已经完成:(a)制造了一种结合活细胞、生物相容性PDMS聚合物衬底和压电PVDF薄膜的生物混合能量收集器;(b)在PDMS上以单轴对齐方向设计活细胞图案,以增强机械驱动;(c)从nrvcm进行长达一个月的连续同步收缩,以进行能量收集演示。本文将详细介绍生物混合能源采集器的概念、设计、制造和实验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Energy harvesting using uniaxially aligned cardiomyocytes
This paper presents the concept of energy harvesting from uniaxially-aligned cardiomyocytes (CMs) on a flexible substrate for the first time. Experimentally, synchronously contracting neonatal rat ventricular cardiomyocytes (NRVCMs) at 0.5Hz have been found to cause the mechanical straining of a piezoelectric energy harvester to produce 87.5nA and 92.3mV of peak current and voltage, respectively. This work has been accomplished: (a) fabrication of a bio-hybrid energy harvester combining living cells, bio-compatible PDMS polymer substrate and piezoelectric PVDF films; (b) engineered living cell patterns on PDMS with uniaxially-aligned direction for enhanced mechanical actuation; and (c) up to one month of continuous synchronous contractions from NRVCMs for energy harvesting demonstration. This paper will detail the concept, design, fabrication, and experiments of the bio-hybrid energy harvester.
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