{"title":"利用单轴排列的心肌细胞收集能量","authors":"Xia Liu, X. Wang, Song Li, Liwei Lin","doi":"10.1109/MEMSYS.2014.6765598","DOIUrl":null,"url":null,"abstract":"This paper presents the concept of energy harvesting from uniaxially-aligned cardiomyocytes (CMs) on a flexible substrate for the first time. Experimentally, synchronously contracting neonatal rat ventricular cardiomyocytes (NRVCMs) at 0.5Hz have been found to cause the mechanical straining of a piezoelectric energy harvester to produce 87.5nA and 92.3mV of peak current and voltage, respectively. This work has been accomplished: (a) fabrication of a bio-hybrid energy harvester combining living cells, bio-compatible PDMS polymer substrate and piezoelectric PVDF films; (b) engineered living cell patterns on PDMS with uniaxially-aligned direction for enhanced mechanical actuation; and (c) up to one month of continuous synchronous contractions from NRVCMs for energy harvesting demonstration. This paper will detail the concept, design, fabrication, and experiments of the bio-hybrid energy harvester.","PeriodicalId":312056,"journal":{"name":"2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS)","volume":"83 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2014-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Energy harvesting using uniaxially aligned cardiomyocytes\",\"authors\":\"Xia Liu, X. Wang, Song Li, Liwei Lin\",\"doi\":\"10.1109/MEMSYS.2014.6765598\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This paper presents the concept of energy harvesting from uniaxially-aligned cardiomyocytes (CMs) on a flexible substrate for the first time. Experimentally, synchronously contracting neonatal rat ventricular cardiomyocytes (NRVCMs) at 0.5Hz have been found to cause the mechanical straining of a piezoelectric energy harvester to produce 87.5nA and 92.3mV of peak current and voltage, respectively. This work has been accomplished: (a) fabrication of a bio-hybrid energy harvester combining living cells, bio-compatible PDMS polymer substrate and piezoelectric PVDF films; (b) engineered living cell patterns on PDMS with uniaxially-aligned direction for enhanced mechanical actuation; and (c) up to one month of continuous synchronous contractions from NRVCMs for energy harvesting demonstration. This paper will detail the concept, design, fabrication, and experiments of the bio-hybrid energy harvester.\",\"PeriodicalId\":312056,\"journal\":{\"name\":\"2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS)\",\"volume\":\"83 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-03-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/MEMSYS.2014.6765598\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MEMSYS.2014.6765598","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Energy harvesting using uniaxially aligned cardiomyocytes
This paper presents the concept of energy harvesting from uniaxially-aligned cardiomyocytes (CMs) on a flexible substrate for the first time. Experimentally, synchronously contracting neonatal rat ventricular cardiomyocytes (NRVCMs) at 0.5Hz have been found to cause the mechanical straining of a piezoelectric energy harvester to produce 87.5nA and 92.3mV of peak current and voltage, respectively. This work has been accomplished: (a) fabrication of a bio-hybrid energy harvester combining living cells, bio-compatible PDMS polymer substrate and piezoelectric PVDF films; (b) engineered living cell patterns on PDMS with uniaxially-aligned direction for enhanced mechanical actuation; and (c) up to one month of continuous synchronous contractions from NRVCMs for energy harvesting demonstration. This paper will detail the concept, design, fabrication, and experiments of the bio-hybrid energy harvester.