H. Takehara, K. Miyazawa, T. Noda, K. Sasagawa, T. Tokuda, Soo Hyeon Kim, R. Iino, H. Noji, J. Ohta
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A CMOS image sensor with low fixed pattern noise suitable for lensless observation system of digital enzyme-linked immunosorbent assay (ELISA)
Digital enzyme-linked immunosorbent assay (ELISA) systems can be miniaturized by applying on-chip CMOS image sensor detection instead of conventional fluorescence microscopy. We have developed a CMOS image sensor dedicated to digital ELISA, which is sensitive to small changes of fluorescent intensity.