异黄酮及其对腹膜透析患者心血管和骨代谢指标的潜在临床影响综述。

IF 1.6 Q3 FOOD SCIENCE & TECHNOLOGY
Zahra Yari
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引用次数: 2

摘要

心血管疾病是慢性肾病患者(包括腹膜透析患者)最重要的死亡原因。氧化应激、全身和血管炎症、脂质异常是这些患者发生心血管疾病的重要原因。骨骼疾病也是透析患者的常见并发症,可导致骨折、生活质量下降、血管钙化、心血管疾病和死亡率增加。对非尿毒症人群的研究表明,大豆异黄酮对氧化应激、炎症、脂质异常和骨代谢标志物有有益作用;然而,这方面的研究很少在腹膜透析患者中进行。本文综述了大豆异黄酮对心血管疾病和骨标志物影响的关键数据,并讨论了大豆异黄酮在预防和控制腹膜透析并发症中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Review of Isoflavones and Their Potential Clinical Impacts on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients.

Review of Isoflavones and Their Potential Clinical Impacts on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients.

Cardiovascular disease is the most important cause of mortality in patients with chronic kidney disease, including patients undergoing peritoneal dialysis. Oxidative stress, systemic and vascular inflammation, and lipid abnormalities are important causes of cardiovascular disease in these patients. Bone disorders are also a common complication in dialysis patients and can lead to bone fractures, decreased quality of life, vascular calcification, cardiovascular disease, and increased mortality. Studies in non-uremic populations have shown that soy isoflavones have beneficial effects on oxidative stress, inflammation, lipid abnormalities, and markers of bone metabolism; however, very few studies in this field have been conducted with peritoneal dialysis patients. This paper reviews the key data regarding the effects of soy isoflavones on cardiovascular disease and bone markers and discusses the role of this nutraceutical in preventing and managing the complications of peritoneal dialysis.

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来源期刊
Preventive Nutrition and Food Science
Preventive Nutrition and Food Science Agricultural and Biological Sciences-Food Science
CiteScore
3.40
自引率
0.00%
发文量
35
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