IgG1糖型及其与FcγRIa (CD64)受体相互作用的研究

IF 1.5 4区工程技术

Journal of Research of the National Institute of Standards and Technology Pub Date : 2021-01-01 DOI:10.6028/jres.126.010

Kyle W Anderson, Kerry Scott, Ioannis L Karageorgos, Elyssia S Gallagher, Venkata S Tayi, Michael Butler, Jeffrey W Hudgens

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引用次数: 1

摘要

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Dataset from HDX-MS Studies of IgG1 Glycoforms and Their Interactions with the FcγRIa (CD64) Receptor.

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Dataset from HDX-MS Studies of IgG1 Glycoforms and Their Interactions with the FcγRIa (CD64) Receptor.

This document presents hydrogen-deuterium exchange mass spectrometry (HDX-MS) data from measurements of three purified IgG1 glycoform samples, predominantly G0F, G2F, and SAF, in isolation and in complexation with the high-affinity receptor, FcγRIa (CD64). The IgG1 antibody used in this study, aIL8hFc, is a murine-human chimeric IgG1, which inhibits IL-8 binding to human neutrophils.

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来源期刊

Journal of Research of the National Institute of Standards and Technology Engineering-General Engineering

自引率

33.30%

发文量

期刊介绍： The Journal of Research of the National Institute of Standards and Technology is the flagship publication of the National Institute of Standards and Technology. It has been published under various titles and forms since 1904, with its roots as Scientific Papers issued as the Bulletin of the Bureau of Standards. In 1928, the Scientific Papers were combined with Technologic Papers, which reported results of investigations of material and methods of testing. This new publication was titled the Bureau of Standards Journal of Research. The Journal of Research of NIST reports NIST research and development in metrology and related fields of physical science, engineering, applied mathematics, statistics, biotechnology, information technology.