Effects of Perfluorocarbon Use during Rhegmatogenous Retinal Detachment Surgery on Postoperative Outcomes.

IF 2.1 4区医学 Q2 OPHTHALMOLOGY

Ophthalmologica Pub Date : 2023-01-01 Epub Date: 2023-06-02 DOI:10.1159/000531342

Masahiko Sugimoto, Maki Kozawa, Yoshitsugu Matsui, Hisashi Matsubara, Mineo Kondo, Taiji Sakamoto

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引用次数: 0

Abstract

Introduction: The aim of this study was to determine whether the use of perfluorocarbon liquid (PFCL) affects the rate of retinal re-attachments after an initial attachment by vitrectomy in eyes with rhegmatogenous retinal detachment (RRD).

Methods: This was a retrospective, observational, multicenter study of 3,446 eyes registered in the Japanese vitreoretinal surgery treatment information database. Of these, 2,648 eyes had undergone vitrectomy as the first surgery for RRD. The re-attachment rates after the primary vitrectomy with or without PFCL were evaluated. In addition, the significance of factors affecting the re-detachments was determined by univariate and multivariate analyses. The measured outcomes were the rates of re-attachments after the primary vitrectomy with or without the use of PFCL.

Results: A total of 2,362 eyes in the database were analyzed: 325 had and 2,037 did not have PFCL injected into the vitreous cavity during the vitrectomy. The rate of re-attachments was 91.5% in the PFCL group and 93.2% in the non-PFCL group (p = 0.46, χ2 test). Although there were several risk factors associated with the re-detachments in eyes without PFCL (p < 0.05, Welch's t tests, and Fisher's exact tests), they were not associated in eyes with PFCL use. However, multivariate analyses showed that there was no significant association between the use and the non-use of PFCL in the rate of re-detachments (β = -0.08, p = 0.46).

Conclusions: The use of PFCL during the initial vitrectomy for RRD does not affect the rate of re-attachments.

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孔源性视网膜脱离手术中使用全氟碳化合物对术后预后的影响。

前言:本研究的目的是确定全氟碳液体(PFCL)的使用是否会影响孔源性视网膜脱离(RRD)眼玻璃体切除术后初次附着的视网膜再附着率。方法:这是一项回顾性、观察性、多中心研究，研究对象为在日本玻璃体视网膜手术治疗信息数据库中登记的3,446只眼睛。其中，2648只眼睛接受了玻璃体切除术作为RRD的第一次手术。评估玻璃体切除术后带或不带PFCL的再附着率。此外，通过单因素分析和多因素分析确定了影响再脱离的因素的显著性。测量的结果是首次玻璃体切除术后使用或不使用PFCL的再附着率。结果:数据库中共有2,362只眼被分析，其中325只眼在玻璃体切割过程中注射了PFCL, 2037只眼没有注射PFCL。PFCL组再附着率为91.5%，非PFCL组为93.2% (p = 0.46， χ2检验)。虽然有几个危险因素与无PFCL的眼睛再脱离相关(p <0.05 (Welch’st检验和Fisher’s精确检验)，它们在眼睛中与PFCL的使用无关。然而，多变量分析显示，使用和不使用PFCL在再脱离率方面没有显著相关性(β = -0.08, p = 0.46)。结论:在RRD的初始玻璃体切除术中使用PFCL不会影响再附着率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmologica 医学-眼科学

CiteScore

5.10

自引率

3.80%

发文量

审稿时长

3 months

期刊介绍： Published since 1899, ''Ophthalmologica'' has become a frequently cited guide to international work in clinical and experimental ophthalmology. It contains a selection of patient-oriented contributions covering the etiology of eye diseases, diagnostic techniques, and advances in medical and surgical treatment. Straightforward, factual reporting provides both interesting and useful reading. In addition to original papers, ''Ophthalmologica'' features regularly timely reviews in an effort to keep the reader well informed and updated. The large international circulation of this journal reflects its importance.