Use of Heavy Silicon Oil as Intraocular Tamponade for Inferior Retinal Detachment Complicated by Proliferative Vitreoretinopathy: A Multicentric Experience.

IF 2.1 4区 医学 Q2 OPHTHALMOLOGY
Ophthalmologica Pub Date : 2023-01-01 Epub Date: 2023-05-26 DOI:10.1159/000531141
Maurizio Mete, Barbara Parolini, Emilia Maggio, Giulia Airaghi, Nicoletta De Santis, Massimo Guerriero, Grazia Pertile
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Abstract

Introduction: This is a multicentric study on the use of heavy silicon oil (HSO) as an intraocular tamponade for inferior retinal detachment (RD) complicated by proliferative vitreoretinopathy (PVR).

Methods: 139 eyes treated for RD with PVR were included in the study. 10 (7.2%) were affected by primary RD with inferior PVR, while 129 (92.8%) were affected by recurrent RD with inferior PVR. 102 eyes (73.9%) had received a silicon oil (SO) tamponade in a previous intervention prior to receiving HSO. Mean follow-up was 36.5 (standard deviation = 32.3) months.

Results: The median interval between HSO injection and removal was 4 months (interquartile range: 3). At the time of HSO removal, the retina was attached in 120 eyes (87.6%), whereas in 17 eyes (12.4%), it had re-detached while the HSO was in situ. 32 eyes (23.2%) showed recurrent RD. A subsequent RD relapse was observed in 14.2% of cases with no RD at the time of HSO removal, and in 88.2% if an RD was present at the time of HSO removal. Advancing age showed a positive association with retinal attachment at the end of follow-up, while the risk of RD relapse at the end of the follow-up showed a significant negative association with HSO tamponade duration and with the use of SO rather than air or gas as post-HSO tamponade materials. Mean best corrected visual acuity was 1.1 logarithm of minimum angle of resolution at all follow-up time points. 56 cases (40.3%) needed treatment for elevated intraocular pressure (IOP), with which no clinically relevant variables were associated during follow-up.

Conclusion: HSO represents a safe and effective tamponade in cases of inferior RD with PVR. The presence of RD at the time of HSO removal is a negative prognostic factor for the development of a subsequent RD relapse. According to our findings, in cases of RD at the time of HSO removal, a short-term tamponade should definitely be avoided, in favor of SO. Special attention must be paid to the risk of IOP elevation, and patients should be closely monitored.

使用重硅油作为眼内填塞治疗下视网膜脱离合并增生性玻璃体视网膜病变:一个多中心的经验。
简介:这是一项多中心研究,使用重硅油(HSO)作为眼内填塞治疗下视网膜脱离(RD)合并增生性玻璃体视网膜病变(PVR)。方法:139只眼采用PVR治疗RD。原发性RD合并下PVR 10例(7.2%),复发性RD合并下PVR 129例(92.8%)。102只眼(73.9%)在接受HSO之前接受过硅油填塞。平均随访36.5个月(标准差= 32.3)。结果:HSO注射至摘除的中位时间间隔为4个月(四分位数间距为3)。摘除HSO时,视网膜附着120只眼(87.6%),而原位HSO再脱离17只眼(12.4%)。32只眼睛(23.2%)出现复发性视网膜病变。14.2%的患者在摘除HSO时没有视网膜病变,88.2%的患者在摘除HSO时存在视网膜病变。年龄的增长与随访结束时视网膜附着呈正相关,而随访结束时RD复发的风险与HSO填塞时间和使用SO而不是空气或气体作为HSO后填塞材料呈显著负相关。在所有随访时间点,平均最佳矫正视力为最小分辨角的1.1对数。56例(40.3%)患者因眼压升高需要治疗,随访无相关临床变量。结论:HSO是一种安全有效的下段RD合并PVR填塞方法。在HSO切除时RD的存在是随后RD复发的负面预后因素。根据我们的研究结果,在HSO切除时发生RD的情况下,应绝对避免短期填塞,而应选择SO。必须特别注意IOP升高的风险,并应密切监测患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Ophthalmologica
Ophthalmologica 医学-眼科学
CiteScore
5.10
自引率
3.80%
发文量
39
审稿时长
3 months
期刊介绍: Published since 1899, ''Ophthalmologica'' has become a frequently cited guide to international work in clinical and experimental ophthalmology. It contains a selection of patient-oriented contributions covering the etiology of eye diseases, diagnostic techniques, and advances in medical and surgical treatment. Straightforward, factual reporting provides both interesting and useful reading. In addition to original papers, ''Ophthalmologica'' features regularly timely reviews in an effort to keep the reader well informed and updated. The large international circulation of this journal reflects its importance.
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