Food selection and processing: Can we blend science with engineering to address Chronic Kidney Disease (CKD)?

Md. Abdul Wazed, Jinat Rabeya, E. F. Ansary, Md Abdul Awale, M. Farid
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Abstract

Chronic kidney disease (CKD) alters the function and structure of the kidney irreversibly, over months or years. The rising incidence of CKD has become a leading global health problem and therefore a number of multi-field investigations are being carried on. In general, diabetes and high blood pressure (hypertension) are the most common causes of CKD. However, the importance of functional food selection and less consumption of ultra-processed food is at the forefront of the current research domain to manage CKD. To address this threat, experts suggest and recommend adopting a science-based dietary pattern, for instance, the Dietary Approaches to Stop Hypertension (DASH). Moreover, food bioactive compounds are non-nutrients that typically occur in small quantities in foods, and hence, the selection of proper food (source) and subsequent processing is of paramount importance to attenuate the magnitude of CKD. The role of food science in managing chronic diseases could be coupled with the advancement of food engineering to minimize the detrimental effect of food processing along with the delivery of target bioactive molecules. This potentially indicates bold ambitions to innovate holistic solutions to address CKD through a proper selection of food and processing parameters.
食品选择和加工:我们能否将科学与工程相结合来解决慢性肾脏疾病(CKD)?
慢性肾脏疾病(CKD)会在数月或数年内不可逆转地改变肾脏的功能和结构。CKD发病率的上升已成为一个主要的全球健康问题,因此正在进行一些多领域的调查。一般来说,糖尿病和高血压(高血压)是CKD最常见的原因。然而,选择功能性食品和减少超加工食品的消费的重要性是当前管理CKD的研究领域的前沿。为了应对这一威胁,专家建议采用一种基于科学的饮食模式,例如,“预防高血压的饮食方法”(DASH)。此外,食品生物活性化合物是非营养素,通常在食品中少量存在,因此,选择适当的食物(来源)和随后的加工对于减轻CKD的程度至关重要。食品科学在慢性病管理中的作用可以与食品工程的进步相结合,以最大限度地减少食品加工以及目标生物活性分子的递送的有害影响。这可能表明,通过正确选择食品和加工参数,创新整体解决方案来解决CKD的大胆雄心。
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