The Association between Dietary Inflammatory Potential and Urologic Cancers: A Meta-analysis

IF 8 1区医学 Q1 NUTRITION & DIETETICS

Advances in Nutrition Pub Date : 2024-01-01 DOI:10.1016/j.advnut.2023.09.012

Ya-nan Dai , Evan Yi-Wen Yu , Maurice P. Zeegers , Anke Wesselius

{"title":"The Association between Dietary Inflammatory Potential and Urologic Cancers: A Meta-analysis","authors":"Ya-nan Dai , Evan Yi-Wen Yu , Maurice P. Zeegers , Anke Wesselius","doi":"10.1016/j.advnut.2023.09.012","DOIUrl":null,"url":null,"abstract":"<div><p>A meta-analysis published in 2018 indicated a significant association between the dietary inflammatory index (DII) and risk of urologic cancers (UC). The number of included studies was limited, and more research has been published on this topic since then. The current study aimed to find a more precise estimate of the association between dietary inflammatory potential and risk of UC by updating the previous meta-analysis. The PubMed and Embase databases were searched between January 2015 and April 2023 to identify eligible articles. Combined relative risk (RR) and 95% confidence intervals (CI) were calculated by random-effects model to assess the association between dietary inflammatory potential and risk of UC by comparison of the highest versus the lowest category of the DII/empirical dietary inflammatory pattern (EDIP) or by using the continuous DII/EDIP score. The analysis, including 23 studies with 557,576 subjects, showed different results for UC. There was a significant association for prostate cancer among case-control studies (RR = 1.75, 95% CI: 1.34-2.28), whereas among cohort studies a null association was found (RR = 1.02, 95% CI: 0.96-1.08). For bladder cancer, a nonsignificant association was observed in both case-control (RR = 1.59, 95% CI: 0.95-2.64) and cohort studies (RR = 1.03, 95% CI: 0.86-1.24). Pooled RR from 3 case-control studies displayed a statistically significant association between the DII and risk of kidney cancer (RR = 1.27, 95% CI: 1.03-1.56). Although DII was positively associated with all types of UC, no association was found for EDIP. The present meta-analysis confirmed that an inflammatory diet has a direct effect on the development of prostate cancer and kidney cancer. Large-scale studies are needed to demonstrate the association between dietary inflammatory potential and risk of UC and provide effective nutritional advice for UC prevention.</p></div><div><h3>Protocol registration</h3><p>The protocol was registered in the International Prospective Register of Systematic Reviews (CRD42023391204).</p></div>","PeriodicalId":7349,"journal":{"name":"Advances in Nutrition","volume":null,"pages":null},"PeriodicalIF":8.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2161831323013856/pdfft?md5=30736836e2ddd5ea9dc769c5fd443861&pid=1-s2.0-S2161831323013856-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Nutrition","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2161831323013856","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}

引用次数: 0

Abstract

A meta-analysis published in 2018 indicated a significant association between the dietary inflammatory index (DII) and risk of urologic cancers (UC). The number of included studies was limited, and more research has been published on this topic since then. The current study aimed to find a more precise estimate of the association between dietary inflammatory potential and risk of UC by updating the previous meta-analysis. The PubMed and Embase databases were searched between January 2015 and April 2023 to identify eligible articles. Combined relative risk (RR) and 95% confidence intervals (CI) were calculated by random-effects model to assess the association between dietary inflammatory potential and risk of UC by comparison of the highest versus the lowest category of the DII/empirical dietary inflammatory pattern (EDIP) or by using the continuous DII/EDIP score. The analysis, including 23 studies with 557,576 subjects, showed different results for UC. There was a significant association for prostate cancer among case-control studies (RR = 1.75, 95% CI: 1.34-2.28), whereas among cohort studies a null association was found (RR = 1.02, 95% CI: 0.96-1.08). For bladder cancer, a nonsignificant association was observed in both case-control (RR = 1.59, 95% CI: 0.95-2.64) and cohort studies (RR = 1.03, 95% CI: 0.86-1.24). Pooled RR from 3 case-control studies displayed a statistically significant association between the DII and risk of kidney cancer (RR = 1.27, 95% CI: 1.03-1.56). Although DII was positively associated with all types of UC, no association was found for EDIP. The present meta-analysis confirmed that an inflammatory diet has a direct effect on the development of prostate cancer and kidney cancer. Large-scale studies are needed to demonstrate the association between dietary inflammatory potential and risk of UC and provide effective nutritional advice for UC prevention.

Protocol registration

The protocol was registered in the International Prospective Register of Systematic Reviews (CRD42023391204).

查看原文本刊更多论文

饮食炎症潜能与泌尿系癌症的关系：荟萃分析。

2018年发表的一项荟萃分析表明，饮食炎症指数（DII）与泌尿系统癌症（UC）风险之间存在显著关联。纳入的研究数量有限，此后发表了更多关于这一主题的研究。目前的研究旨在通过更新先前的荟萃分析，找到更准确的估计饮食炎症潜能与UC风险之间的关系。PubMed和Embase数据库在2015年1月至2023年4月期间进行了搜索，以确定符合条件的文章。通过随机效应模型计算组合相对风险（RR）和95%置信区间（CI），通过比较DII/EDIP的最高和最低类别或使用连续DII/EDIP评分来评估饮食炎症潜能与UC风险之间的相关性。该分析包括23项对557576名受试者的研究，显示UC的结果不同。在病例对照研究中，前列腺癌症有显著相关性（RR=1.75，95%CI:1.34-2.28），而在队列研究中，发现无相关性（RR=0.02，95%CI:0.96-1.08），在病例对照研究（RR=1.59，95%CI:0.95-2.64）和队列研究中均观察到无显著相关性（RR=1.03，95%CI=0.86-12.4）。3项病例对照研究的汇总RR显示DII与癌症风险之间存在统计学显著相关性（RR=1.27，95%CI:1.03-1.56）。尽管DII与所有类型的UC呈正相关，没有发现EDIP的关联。目前的荟萃分析证实，炎症饮食对前列腺癌症和癌症的发展有直接影响。需要进行大规模研究来证明饮食炎症潜能与UC风险之间的关系，并为UC预防提供有效的营养建议。方案注册：该方案已在国际前瞻性系统评价注册中心（CRD42023391204）注册。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Advances in Nutrition 医学-营养学

CiteScore

17.40

自引率

2.20%

发文量

117

审稿时长

56 days

期刊介绍： Advances in Nutrition (AN/Adv Nutr) publishes focused reviews on pivotal findings and recent research across all domains relevant to nutritional scientists and biomedical researchers. This encompasses nutrition-related research spanning biochemical, molecular, and genetic studies using experimental animal models, domestic animals, and human subjects. The journal also emphasizes clinical nutrition, epidemiology and public health, and nutrition education. Review articles concentrate on recent progress rather than broad historical developments. In addition to review articles, AN includes Perspectives, Letters to the Editor, and supplements. Supplement proposals require pre-approval by the editor before submission. The journal features reports and position papers from the American Society for Nutrition, summaries of major government and foundation reports, and Nutrient Information briefs providing crucial details about dietary requirements, food sources, deficiencies, and other essential nutrient information. All submissions with scientific content undergo peer review by the Editors or their designees prior to acceptance for publication.