Isolation and identification of a bioactive compound from Japanese red pine (Pinus densiflora) tea and its antioxidative effects on vascular endothelial cells

IF 4.1 Q2 FOOD SCIENCE & TECHNOLOGY
WenQian Jiang , Yuka Hattori , WonJune Lee , YiQian Zhang , KaiNing Zhang , Shojiro Hishiyama , Tomoko Shimokawa , Hitoshi Miyazaki , Shigeki Yoshida
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引用次数: 0

Abstract

The bioactive compound, which showed a potent nitric oxide production stimulation effect, was isolated from Japanese red pine tea and identified as (+)-catechin. Compared with (−)-epigallocatechin 3-O-gallate and (−)-catechin, (+)-catechin exhibited greater NO production promotion and protection from H2O2-induced oxidative stress in vascular endothelial cells. The (+)-catechin content of Japanese red pine tea was found to be higher than that of buckwheat or green tea, both of which are known to contain (+)-catechin. This study indicated that (+)-catechin could be used as a potential functional ingredient for endothelium function protection and provides a basis for the use of red pine tea in endothelium dysfunction prevention in the future.

Abstract Image

赤松茶活性成分的分离鉴定及其对血管内皮细胞的抗氧化作用
从日本红松茶中分离得到具有强烈刺激一氧化氮生成作用的生物活性化合物,鉴定为(+)-儿茶素。与(−)-表没食子儿茶素3-O-没食子酸盐和(−)儿茶素相比,(+)-儿茶素在血管内皮细胞中表现出更大的NO生成促进作用和对H2O2诱导的氧化应激的保护作用。日本红松茶的(+)-儿茶素含量高于荞麦或绿茶,这两种茶都含有(+)儿茶素。本研究表明,(+)-儿茶素可作为一种潜在的保护内皮功能的功能成分,为赤松茶在未来预防内皮功能障碍中的应用提供了基础。
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来源期刊
NFS Journal
NFS Journal Agricultural and Biological Sciences-Food Science
CiteScore
11.10
自引率
0.00%
发文量
18
审稿时长
29 days
期刊介绍: The NFS Journal publishes high-quality original research articles and methods papers presenting cutting-edge scientific advances as well as review articles on current topics in all areas of nutrition and food science. The journal particularly invites submission of articles that deal with subjects on the interface of nutrition and food research and thus connect both disciplines. The journal offers a new form of submission Registered Reports (see below). NFS Journal is a forum for research in the following areas: • Understanding the role of dietary factors (macronutrients and micronutrients, phytochemicals, bioactive lipids and peptides etc.) in disease prevention and maintenance of optimum health • Prevention of diet- and age-related pathologies by nutritional approaches • Advances in food technology and food formulation (e.g. novel strategies to reduce salt, sugar, or trans-fat contents etc.) • Nutrition and food genomics, transcriptomics, proteomics, and metabolomics • Identification and characterization of food components • Dietary sources and intake of nutrients and bioactive compounds • Food authentication and quality • Nanotechnology in nutritional and food sciences • (Bio-) Functional properties of foods • Development and validation of novel analytical and research methods • Age- and gender-differences in biological activities and the bioavailability of vitamins, minerals, and phytochemicals and other dietary factors • Food safety and toxicology • Food and nutrition security • Sustainability of food production
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