Effects of Nut Consumption on Cardiovascular Risk Factors and Coronary Heart Diseases

IF 1.3 Q4 FOOD SCIENCE & TECHNOLOGY

Functional Foods in Health and Disease Pub Date : 2022-11-17 DOI:10.31989/ffhd.v12i11.1022

M. Zibaeenezhad, Zahra Elyaspour

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引用次数: 0

Abstract

Background: Intervention and epidemiological studies have shown that nut consumption has beneficial effects on cardiovascular risk factors, such as hypertension, type 2 diabetes, body mass index, and hyperlipidemia. The aim of this review is to investigate the effects of nut consumption on cardiovascular risk factors and coronary heart diseases. In addition, we investigated possible mediating mechanisms through which nuts act with health protective effects, which could have a preventive effect on cardiovascular risk factors and coronary artery diseases.Method: We collected accredited international investigations, whether original, review, meta-analysis that published data in Google Scholar, PubMed/Medline, Wiley Online Library, Web of Science, Science Direct, Scopus, and Research Gate databases.Result:Some human studies and most animal and laboratory studies reported that favorable effects of nut consumption on cardiovascular risk factors and diseases are through their nutrient profile including polyphenols, unsaturated fatty acid, vitamins, phytosterols, minerals, fibers, and protein. Nut nutrient profile could act through reduction inflammation, inhibition oxidative stress, gut microbiota modification, improvement of endothelial function, modulating gene expression, miRNA, adipokines, insulin secretion, lipid and glucose metabolism, and decreasing cholesterol absorption.Conclusion:Nuts have favorably acted on lipid profile, glucose homeostasis, vascular health, and weight control. Furthermore, human clinical trials are needed to find the exact and most effective pathways by which nuts prevent or reduce cardiovascular risk factors.Keywords: Nut Consumption, hypertension, type 2 diabetes, body mass index, hyperlipidemia

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坚果消费对心血管危险因素和冠心病的影响

背景:干预和流行病学研究表明，坚果消费对心血管危险因素，如高血压、2型糖尿病、体重指数和高脂血症有有益的影响。本综述的目的是探讨坚果消费对心血管危险因素和冠心病的影响。此外，我们还研究了坚果具有健康保护作用的可能中介机制，坚果可能对心血管危险因素和冠状动脉疾病具有预防作用。方法:我们收集了经过认证的国际调查，包括谷歌Scholar、PubMed/Medline、Wiley Online Library、Web of Science、Science Direct、Scopus和Research Gate数据库中发表的原始、综述和荟萃分析数据。结果:一些人类研究和大多数动物和实验室研究报告说，食用坚果对心血管危险因素和疾病的有利影响是通过它们的营养成分，包括多酚、不饱和脂肪酸、维生素、植物甾醇、矿物质、纤维和蛋白质。坚果营养成分可通过减少炎症、抑制氧化应激、改变肠道微生物群、改善内皮功能、调节基因表达、miRNA、脂肪因子、胰岛素分泌、脂质和糖代谢以及降低胆固醇吸收等途径发挥作用。结论:坚果对血脂、葡萄糖稳态、血管健康和体重控制有良好的作用。此外，需要进行人体临床试验，以找到坚果预防或减少心血管危险因素的准确和最有效的途径。关键词:坚果消费，高血压，2型糖尿病，体重指数，高脂血症

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来源期刊

Functional Foods in Health and Disease FOOD SCIENCE & TECHNOLOGY-

CiteScore

2.20

自引率

20.00%

发文量