Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology.

Lindsey Dzierozynski, Jessica Queen, Cynthia L Sears
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Abstract

Although environmental impacts on the host microbiome have been well studied, it is less certain whether and how host genetics impact the microbiome. This commentary discusses current literature supporting host genetic influences on resident species and pathogenic microbes. Mechanistic experimental studies are warranted to understand host gene-microbiome interplay.

宿主基因对肠道微生物组的微妙而持久的塑造:宿主生物学的关键决定因素。
尽管环境对宿主微生物组的影响已经得到了很好的研究,但宿主遗传学是否以及如何影响微生物组还不太确定。这篇评论讨论了当前支持宿主基因对常驻物种和病原微生物影响的文献。机制实验研究有助于了解宿主基因-微生物组的相互作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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