Multimodal imaging diagnosis for bone fibrous dysplasia malignant transformation: A case report.

IF 2.3 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Biomedical reports Pub Date : 2023-09-01 eCollection Date: 2023-10-01 DOI:10.3892/br.2023.1655
Jian-Lin Lu, Miao Ke, Xiao-Yan Yuan, Jin-Shan Zhang
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引用次数: 0

Abstract

Fibrous dysplasia of bone (FDB) is a rare benign condition in which fibrous tissue replaces normal bone architecture. FDB rarely undergoes malignant transformation, but there are reports of locally aggressive fibrous dysplasia with cortical destruction and soft tissue extension. Diagnosis of FDB malignant transformation is not easy, especially in monostotic form, because of the overlap in imaging features of locally aggressive fibrous dysplasia and fibrous dysplasia with malignant transformation. The present case study reports a rare case of FDB in a 23-year-old man with polyostotic fibrous dysplasia arising in the left side of the pelvis and lower limb bones with partial transformation to fibrosarcoma. This study explored the multimodal imaging features of FDB malignant transformation, to achieve early detection and improve diagnostic accuracy of local FDB aggressiveness and its malignant transformation.

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骨纤维发育不良恶变的多模式影像学诊断:一例报告。
骨纤维发育不良(FDB)是一种罕见的良性疾病,其中纤维组织取代了正常的骨结构。FDB很少发生恶性转化,但有报道称局部侵袭性纤维发育不良伴皮质破坏和软组织延伸。FDB恶变的诊断并不容易,尤其是在单细胞形式下,因为局部侵袭性纤维发育不良和纤维发育不良与恶变的影像学特征重叠。本病例研究报告了一例罕见的FDB病例,该病例发生在一名23岁男子身上,该男子患有骨盆左侧和下肢骨多发性纤维发育不良,部分转化为纤维肉瘤。本研究探讨了FDB恶变的多模式影像学特征,以实现对局部FDB侵袭性及其恶变的早期发现和提高诊断准确性。
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来源期刊
Biomedical reports
Biomedical reports MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
4.10
自引率
0.00%
发文量
86
期刊介绍: Biomedical Reports is a monthly, peer-reviewed journal, dedicated to publishing research across all fields of biology and medicine, including pharmacology, pathology, gene therapy, genetics, microbiology, neurosciences, infectious diseases, molecular cardiology and molecular surgery. The journal provides a home for original research, case reports and review articles.
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