Lijuan Luo, Nan Shen, Wenjuan Chen, Chengjuan Luo, Xiaohang Huang, Yuelian Jiang, Qing Cao
{"title":"<i>Toxoplasma gondii</i> infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review.","authors":"Lijuan Luo, Nan Shen, Wenjuan Chen, Chengjuan Luo, Xiaohang Huang, Yuelian Jiang, Qing Cao","doi":"10.1002/ped4.12290","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Toxoplasmosis is a life-threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about <i>Toxoplasma</i> infection.</p><p><strong>Case presentation: </strong>We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next-generation sequencing (mNGS) after HSCT in a boy. Additionally, we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed.</p><p><strong>Conclusion: </strong>Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre-transplant screening and post-transplant monitoring and prevention in future according to the national conditions of our country.</p>","PeriodicalId":19992,"journal":{"name":"Pediatric Investigation","volume":"5 3","pages":"239-243"},"PeriodicalIF":1.9000,"publicationDate":"2021-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/14/07/PED4-5-239.PMC8458717.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Investigation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/ped4.12290","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/9/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Toxoplasmosis is a life-threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection.
Case presentation: We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next-generation sequencing (mNGS) after HSCT in a boy. Additionally, we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed.
Conclusion: Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre-transplant screening and post-transplant monitoring and prevention in future according to the national conditions of our country.
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