Intersecting alcohol use and depression impedes HIV treatment in the rural South, USA.

IF 2 4区医学 Q3 BEHAVIORAL SCIENCES

Behavioral Medicine Pub Date : 2022-07-01 Epub Date: 2020-10-14 DOI:10.1080/08964289.2020.1809336

Seth C Kalichman, Harold Katner, Ellen Banas, Marnie Hill, Moira O Kalichman

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引用次数: 1

Abstract

This study tested the hypothesis that the co-occurrence of alcohol use and depressive symptoms predicts HIV suppression and antiretroviral therapy (ART) adherence among people living with HIV. Baseline cross-sectional results showed a significant interaction between depressive symptoms and alcohol use in predicting HIV suppression; individuals who drank more alcohol and had higher depressive symptoms demonstrated poorer HIV suppression relative to those who had fewer depressive symptoms. In a one-year longitudinal analysis of ART adherence, alcohol use and depressive symptoms measured in daily text-message assessments demonstrated that neither alcohol use nor depressive symptoms alone predicted ART adherence. However, the intersection of alcohol use on days when experiencing depressive symptoms did significantly predict ART non-adherence, for both moderate and heavy alcohol drinkers. Findings suggest that the co-occurrence of alcohol use and depressive symptoms is a robust predictor of poor HIV treatment outcomes.

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在美国南部的农村，酒精使用和抑郁症阻碍了艾滋病毒的治疗。

这项研究验证了这样一种假设，即酒精使用和抑郁症状的共同出现预示着艾滋病毒感染者的艾滋病毒抑制和抗逆转录病毒治疗(ART)的依从性。基线横断面结果显示，抑郁症状和酒精使用在预测HIV抑制方面存在显著的相互作用;与抑郁症状较少的人相比，饮酒较多、抑郁症状较重的人对艾滋病毒的抑制较差。在一项为期一年的抗逆转录病毒治疗依从性纵向分析中，每日短信评估中测量的酒精使用和抑郁症状表明，酒精使用和抑郁症状都不能单独预测抗逆转录病毒治疗依从性。然而，对于中度和重度饮酒者来说，在出现抑郁症状的日子里饮酒的交叉点确实显著地预测了抗逆转录病毒治疗的不依从性。研究结果表明，酒精使用和抑郁症状的共同出现是艾滋病毒治疗结果不佳的有力预测因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Behavioral Medicine 医学-行为科学

CiteScore

5.30

自引率

4.30%

发文量

审稿时长

>12 weeks

期刊介绍： Behavioral Medicine is a multidisciplinary peer-reviewed journal, which fosters and promotes the exchange of knowledge and the advancement of theory in the field of behavioral medicine, including but not limited to understandings of disease prevention, health promotion, health disparities, identification of health risk factors, and interventions designed to reduce health risks, ameliorate health disparities, enhancing all aspects of health. The journal seeks to advance knowledge and theory in these domains in all segments of the population and across the lifespan, in local, national, and global contexts, and with an emphasis on the synergies that exist between biological, psychological, psychosocial, and structural factors as they related to these areas of study and across health states. Behavioral Medicine publishes original empirical studies (experimental and observational research studies, quantitative and qualitative studies, evaluation studies) as well as clinical/case studies. The journal also publishes review articles, which provide systematic evaluations of the literature and propose alternative and innovative theoretical paradigms, as well as brief reports and responses to articles previously published in Behavioral Medicine.