[Developmental psychopathological characteristics of obsessive-compulsive disorder].

Q3 Pharmacology, Toxicology and Pharmaceutics
Neuropsychopharmacologia Hungarica Pub Date : 2020-09-01
Adrienn Kertesz, Marton Kiss-Leizer, Istvan Szalma, Gabriella Vizin
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引用次数: 0

Abstract

According to the currently available research data obsessive-compulsive disorder (OCD)is a disorder of multifactorial etiology, the causes of which include biological, genetic and environmental-social factors alike. Based on an etiology of that kind, it is justifiable to conduct a developmental psychopathological review of OCD, which may lead, through an exploration of the different factors involved, to a deeper understanding of the disorder's overall nature and specific characteristics, as well as to the development of the most efficient therapies possible. The main objective of the present comprehensive study is the developmental psychopathological analysis of the OCD, including the review of the evolutionary approaches and genetic and environmental factors, as well as an exploration of OCD's age-specific forms of manifestation, based on the recent research results and analyses available in the professional literature. According to our present knowledge, the genetic linkage of early-onset OCD is greater than that of the late-onset variant, as the onset of the syndrome can be attributed to genetic factors to the extent of 40-60%, coupled with the contribution of environmental factors like perinatal disorders, reproductive cycle, childhood infections, familial circumstances, age of the parents and traumatic life events. Evolutionary theories address OCD from a functional perspective. They strive to attribute it primarily to individual or group selection theories that a quite heterogeneous OCD syndrome, which is therapeutically difficult to change, remains to present itself with close to identical, invariably high prevalence in all cultures despite the difficulties. Obsessive-compulsive disorder is present in all ages, and it is often difficult to determine whether we are faced with a healthy or a pathological behavior, as certain obsessive phenomena may appear as part of normal development. The analysis of OCD's etiology, a better understanding of the respective function of specific symptoms, a thorough exploration of age-specific variants of the disorder, i.e. a developmental psychopathological analysis of OCD, is of key importance from diagnostic, therapeutic and vocational rehabilitation aspects alike.

[强迫症的发展精神病理特征]。
根据现有的研究资料,强迫症是一种多因素的疾病,其病因包括生物因素、遗传因素和环境社会因素等。基于这种病因学,我们有理由对强迫症进行发展精神病理学回顾,这可能会通过探索所涉及的不同因素,更深入地了解这种疾病的整体性质和具体特征,并开发出最有效的治疗方法。本综合研究的主要目标是强迫症的发展精神病理学分析,包括对进化方法和遗传和环境因素的回顾,以及强迫症的年龄特异性表现形式的探索,基于最近的研究结果和专业文献的分析。据我们目前所知,早发性OCD的遗传连锁大于晚发性OCD,因为该综合征的发病可归因于遗传因素的程度为40-60%,再加上围产期疾病、生殖周期、儿童感染、家庭环境、父母年龄和创伤性生活事件等环境因素的贡献。进化理论从功能的角度来解决强迫症。他们努力将其主要归因于个体或群体选择理论,即一种非常异质的强迫症综合征,在治疗上很难改变,尽管困难重重,但在所有文化中仍然以接近相同的、不可避免的高患病率呈现出来。强迫症存在于所有年龄段,通常很难确定我们面对的是健康还是病态的行为,因为某些强迫现象可能作为正常发展的一部分出现。分析强迫症的病因,更好地了解特定症状的各自功能,深入探索强迫症的年龄特异性变异,即强迫症的发展精神病理学分析,从诊断、治疗和职业康复方面都至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neuropsychopharmacologia Hungarica
Neuropsychopharmacologia Hungarica Medicine-Medicine (all)
CiteScore
1.60
自引率
0.00%
发文量
8
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