Vaginoplasty Using Human Amniotic Membranes A Report of Five Patients.

IF 0.2 4区医学 Q4 Medicine

生殖医学杂志 Pub Date : 2016-09-01

Ayse Filiz Avsar, Emre Erdem Tas, Hiiseyin Levent Keskin, Gülin Feykan Yeğin

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引用次数: 0

Abstract

Objective: To present our experiences with an innovative surgical approach for vaginal agenesis that uses amnion as the allograft to create a functional neovagina.

Study design: This study involved 5 patients with diagnosed vaginal agenesis. One patient had karyotype 46,XY and was diagnosed with complete androgen insensitivity syn- drome, whereas the others had karyotype 46,XX and were diagnosed with Mayer-Rokitansky-Kiister-Hauser syndrome. All patients underwent Mclndoe vagino- plasty using amnion and were followed up at 2 weeks, 3 months, 6 months, and 12 months postsurgery. Functionality of the neovagina was assessed by Rosen Female Sexual Function Index (FSFI) questionnaire.

Results: At the 12-month follow-up 1 patient report- ed. an inability to use the vaginal dilator effectively; for the other 4 patients the mean depth of the neovagina was 9.5 cm and the mean width was 3.5 cm. The mean overall FSFI score was 28.3.

Conclusion: McIndoe vaginoplasty is a simple, safe, and quick operative method that results in a ftnctional vagina. The amnion is a suitable material to apply to the surface of the neovagina because it is readily avail- able and does not have any associated immune reiection problems or costs.

本刊更多论文

人羊膜阴道成形术附5例报告。

目的:介绍一种利用羊膜作为同种异体移植物创造功能性新阴道的创新阴道发育不全手术方法的经验。研究设计:本研究纳入5例诊断为阴道发育不全的患者。1例患者核型为46,XY，诊断为完全雄激素不敏感综合征，而其他患者核型为46,XX，诊断为Mayer-Rokitansky-Kiister-Hauser综合征。所有患者均行羊膜麦克伦多阴道成形术，术后2周、3个月、6个月、12个月随访。采用罗森女性性功能指数(Rosen Female Sexual Function Index, FSFI)问卷评估新阴道功能。结果:随访12个月，1例患者报告不能有效使用阴道扩张器;4例患者新阴道平均深度9.5 cm，平均宽度3.5 cm。FSFI总分平均为28.3分。结论:麦克氏阴道成形术是一种简单、安全、快速的手术方法，可获得阴道功能。羊膜是一种适用于新阴道表面的合适材料，因为它很容易获得，并且没有任何相关的免疫排斥问题或成本。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

生殖医学杂志医学-妇产科学

自引率

0.00%

发文量

6427

审稿时长

6-12 weeks

期刊介绍： The Journal of Reproductive Medicine® has been the essential tool of Obstetricians and Gynecologists since 1968. As a highly regarded professional journal and the official periodical of six medical associations, JRM® brings timely and relevant information on the latest procedures and advances in the field of reproductive medicine. Published bimonthly, JRM® contains peer-reviewed articles and case reports submitted by top specialists. Common topics include research, clinical practice, and case reports related to general obstetrics and gynecology, infertility, female cancers, gynecologic surgery, contraception, and medical education.