Effect of Varicocele Repair in Patients with Nonobstructive Azoospermia.

IF 0.2 4区医学 Q4 Medicine

生殖医学杂志 Pub Date : 2017-05-01

Teppei Takeshima, Yasushi Yumura, Shinnosuke Kuroda, Yoshitake Kato, Kazumi Noguchi, Akira Iwasaki

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引用次数: 0

Abstract

OBJECTIVE: To evaluate the efficacy of varicocele repair in patients with nonobstructive azoospermia. STUDY DESIGN: Ten patients with nonobstructive azoospermia and clinical varicoceles who underwent varicocele repair were retrospectively investigated. According to the postoperative appearance of motile spermatozoa in the ejaculate, the patients were divided into 2 groups: Responder and Nonresponder. The outcomes of each group were investigated. RESULTS: There were 4 (40%) patients in the Responder group. Serum follicle-stimulating hormone levels were significantly higher in the Nonresponder group than in the Responder group (19.9±6.4 IU/mL vs. 10.8± 4.0 IU/mL, p<0.05). Mean sperm concentration was 5.4 million spermatozoa/mL in the Responder group. One patient achieved a spontaneous pregnancy, and another achieved an assisted pregnancy. In the Nonresponder group 5 patients underwent microdissection testicular sperm extraction (micro-TESE) postoperatively. In 1 patient, motile spermatozoa were successfully retrieved. Histopathological findings in the other 4 patients were Sertoli-cell-only. CONCLUSION: The present study suggested that varicocele repair could be considered in men with nonobstructive azoospermia who have clinical varicoceles. Moreover, varicocele repair seemed to improve sperm retrieval rate during micro-TESE for those in the Nonresponder group.

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精索静脉曲张修复在非梗阻性无精子症患者中的作用。

目的:评价精索静脉曲张修复治疗非阻塞性无精子症的疗效。研究设计:对10例接受精索静脉曲张修复术的非阻塞性无精子症和临床精索静脉曲张患者进行回顾性研究。根据术后射精中运动精子的出现情况，将患者分为有反应组和无反应组。观察各组结果。结果:应答组有4例(40%)患者。无反应组血清促卵泡激素水平显著高于反应组(19.9±6.4 IU/mL vs. 10.8±4.0 IU/mL, p

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来源期刊

生殖医学杂志医学-妇产科学

自引率

0.00%

发文量

6427

审稿时长

6-12 weeks

期刊介绍： The Journal of Reproductive Medicine® has been the essential tool of Obstetricians and Gynecologists since 1968. As a highly regarded professional journal and the official periodical of six medical associations, JRM® brings timely and relevant information on the latest procedures and advances in the field of reproductive medicine. Published bimonthly, JRM® contains peer-reviewed articles and case reports submitted by top specialists. Common topics include research, clinical practice, and case reports related to general obstetrics and gynecology, infertility, female cancers, gynecologic surgery, contraception, and medical education.