8 weeks versus 12 weeks of sofosbuvir–velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India

Amit Goel DM, Sumit Rungta DM, Vinod Kumar DM, Shalimar DM, Ajay Kumar DM, Harshita Katiyar MSc, Surender Singh DM, Amar Deep PhD, Ajay Kumar Mishra DM, Ashish Awasthi PhD, Vikasendu Agarwal MD, Anurag Kumar Tiwari DM, Dawesh Prakash Yadav DM, Sunit Kumar Shukla DM, Ujjwal Sonika DM, Radha Krishan Dhiman DM, Bharat Bhushan Rewari MD, Prof Rakesh Aggarwal DM
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引用次数: 0

Abstract

Chronic hepatitis C virus (HCV) infection without cirrhosis can be treated with 12 weeks of sofosbuvir–velpatasvir combination therapy. We aimed to assess whether a shorter 8-week treatment regimen of this combination was non-inferior to the standard 12-week regimen in successfully clearing HCV infection in HCV-infected patients without evidence of cirrhosis.
8周vs 12周sofosbuvir-velpatasvir治疗初治、非肝硬化慢性丙型肝炎(RESOLVE):印度的一项多中心、开放标签、非效性、随机对照试验
无肝硬化的慢性丙型肝炎病毒(HCV)感染可通过12周的索非布韦-维帕他韦联合治疗。我们的目的是评估在无肝硬化证据的HCV感染患者中,较短的8周联合治疗方案在成功清除HCV感染方面是否优于标准的12周治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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