Advances in the Development, Enzymatic Preparation, and Functional Properties of Human Milk Fat Substitutes

IF 2.4 4区农林科学 Q3 CHEMISTRY, APPLIED

Journal of the American Oil Chemists Society Pub Date : 2026-08-06 Epub Date: 2026-05-14 DOI:10.1002/aocs.70097

Yunjing Wu, Yun Han, Jingjing Lun, Xing Qiao, Yanlan Bi, Linshang Zhang

引用次数: 0

Abstract

1,3-diunsaturated-2-palmitoyl-glycerol (UPU structured lipids) demonstrate considerable potential as substitutes for human milk fat, effectively meeting the nutritional and developmental requirements of infants. This review outlines the development of human milk fat substitutes and examines how lipase synthesis strategies influence the production of UPU structured lipids. The review also analyzes the functional properties of these lipids in relation to types of lipases, acyl acceptors, and acyl donors. Finally, building on the well-established structure–function relationships of these lipids, we offer insights into future research and development directions, with a focus on 1,3-diunsaturated-2-saturated triglyceride (USU structured lipids) and customizing personalized UPU structured lipids products.

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乳脂代用品的开发、酶促制备及功能特性研究进展

1,3-不饱和-2-棕榈酰甘油（UPU结构脂）显示出作为人类乳脂替代品的巨大潜力，有效地满足婴儿的营养和发育需求。本文综述了人乳脂肪替代品的发展，并探讨了脂肪酶合成策略如何影响UPU结构脂质的生产。本文还分析了这些脂质的功能特性与脂肪酶类型、酰基受体和酰基供体的关系。最后，基于这些脂质的结构-功能关系，我们提出了未来的研究和发展方向，重点是1,3-不饱和-2-饱和甘油三酯（USU结构脂）和定制个性化的UPU结构脂产品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the American Oil Chemists Society 工程技术-食品科技

CiteScore

4.10

自引率

5.00%

发文量

审稿时长

2.4 months

期刊介绍： The Journal of the American Oil Chemists’ Society (JAOCS) is an international peer-reviewed journal that publishes significant original scientific research and technological advances on fats, oils, oilseed proteins, and related materials through original research articles, invited reviews, short communications, and letters to the editor. We seek to publish reports that will significantly advance scientific understanding through hypothesis driven research, innovations, and important new information pertaining to analysis, properties, processing, products, and applications of these food and industrial resources. Breakthroughs in food science and technology, biotechnology (including genomics, biomechanisms, biocatalysis and bioprocessing), and industrial products and applications are particularly appropriate. JAOCS also considers reports on the lipid composition of new, unique, and traditional sources of lipids that definitively address a research hypothesis and advances scientific understanding. However, the genus and species of the source must be verified by appropriate means of classification. In addition, the GPS location of the harvested materials and seed or vegetative samples should be deposited in an accredited germplasm repository. Compositional data suitable for Original Research Articles must embody replicated estimate of tissue constituents, such as oil, protein, carbohydrate, fatty acid, phospholipid, tocopherol, sterol, and carotenoid compositions. Other components unique to the specific plant or animal source may be reported. Furthermore, lipid composition papers should incorporate elements of yeartoyear, environmental, and/ or cultivar variations through use of appropriate statistical analyses.