Clinically Meaningful Improvement Across Ages 50-95 Years After Decompression Without Fusion for Central Lumbar Spinal Stenosis Without Spondylolisthesis.

IF 5 2区 医学 Q1 CLINICAL NEUROLOGY
Neurospine Pub Date : 2026-07-01 Epub Date: 2026-07-31 DOI:10.14245/ns.26520722.0361
Henrik Damm, Magnus K Karlsson, Lars Jehpsson, Niyaz Hareni, Björn E Rosengren
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Abstract

Objective: Advanced age has been proposed as a risk factor for worse outcomes and higher complication rates after spinal surgery. We assessed whether decompression for central lumbar spinal stenosis (CLSS) provided meaningful improvement in patients aged 50-95 years.

Methods: We evaluated preoperative and 1-year postoperative Numerical Rating Scale (NRS) leg and back pain, Oswestry Disability Index (ODI), and complications in 17,987 patients aged ≥50 years undergoing decompression without fusion for CLSS without spondylolisthesis from the Swespine register. Meaningful improvement was defined using minimal clinically important difference (MCID) thresholds for NRS leg/back pain and ODI. Across 5-year age groups, we assessed the proportions improving ≥MCID and odds ratios (ORs) with 95% confidence intervals (CIs), using ages 65-69 years as the reference group.

Results: Across age groups, 71%-80% improved ≥MCID in ≥1 outcome. Compared with the reference group, ORs (95% CI) for ≥MCID improvement were lower in ages 70-74 (0.8; 0.7-1.0), 75-79 (0.7; 0.6-0.8), 80-84 (0.6; 0.5-0.7), and 85-89 (0.6; 0.5-0.8); no other age groups differed. 5%-12% experienced complications. Compared with the reference group, ORs (95% CI) for complications were higher in ages 75-79 (1.3; 1.1-1.6), 80-84 (1.7; 1.4-2.1), and 85-89 (2.0; 1.5-2.8), and lower in ages 55-59 (0.7; 0.5-0.9).

Conclusion: 77% of patients aged 50-95 years improved ≥MCID after decompression without fusion for CLSS without spondylolisthesis. Although outcomes were slightly worse and complication rates higher in older than younger patients, decompression without fusion remains effective across this age range.

50-95岁无椎体滑脱的中枢性腰椎管狭窄减压无融合术后临床意义的改善。
目的:高龄已被认为是脊柱手术后预后较差和并发症发生率较高的危险因素。我们评估了中枢性腰椎管狭窄减压(CLSS)是否对50-95岁的患者有意义的改善。方法:我们评估了术前和术后1年的数值评定量表(NRS)腿部和背部疼痛,Oswestry残疾指数(ODI),以及来自Swespine登记的17,987例年龄≥50岁,接受无椎滑脱CLSS减压无融合的患者的并发症。使用NRS腿/背部疼痛和ODI的最小临床重要差异(MCID)阈值来定义有意义的改善。在5年年龄组中,我们以65-69岁为参照组,评估≥MCID改善的比例和95%置信区间(ci)的优势比(ORs)。结果:在各年龄组中,≥1个结局的≥MCID改善率为71%-80%。与对照组相比,70-74岁(0.8;0.7-1.0)、75-79岁(0.7;0.6-0.8)、80-84岁(0.6;0.5-0.7)和85-89岁(0.6;0.5-0.8)患者≥MCID改善的or (95% CI)较低;其他年龄组没有差异。5%-12%出现并发症。与对照组相比,75 ~ 79岁(1.3;1.1 ~ 1.6)、80 ~ 84岁(1.7;1.4 ~ 2.1)和85 ~ 89岁(2.0;1.5 ~ 2.8)并发症的or (95% CI)较高,55 ~ 59岁(0.7;0.5 ~ 0.9)并发症的or (95% CI)较低。结论:50-95岁的CLSS患者中,77%的患者在无椎滑脱的CLSS减压不融合后改善≥MCID。尽管老年患者的预后略差,并发症发生率高于年轻患者,但在这个年龄范围内,无融合减压仍然有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neurospine
Neurospine Multiple-
CiteScore
5.80
自引率
18.80%
发文量
93
审稿时长
10 weeks
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