Are Bioimpedance Parameters Altered in Adults With Down Syndrome? A Cross-Sectional Study

IF 2.4 2区医学 Q1 EDUCATION, SPECIAL

Journal of Intellectual Disability Research Pub Date : 2026-09-08 Epub Date: 2026-07-07 DOI:10.1111/jir.70143

Anselmo de Athayde Costa e Silva, María Carbó-Carreté, Casimiro Javierre, Joan Guàrdia-Olmo, Stamatis Agiovlasitis, Guillermo R. Oviedo

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引用次数: 0

Abstract

Background

Individuals with Down syndrome (DS) exhibit altered body composition that could be assessed through bioelectrical impedance analysis (BIA). This study aims to compare the BIA measures and bioelectrical impedance vector analysis (BIVA) between individuals with and without DS.

Methods

We evaluated 46 individuals with and 46 without DS through BIA and BIVA. We employed generalized linear models (GLM) to assess the effects of group and sex on BIA, adjusting by age and height.

Results

Individuals with DS had lower whole-body resistance/height (DS: 332.1 ± 51.1; non-DS: 349.0 ± 57.5 Ω/m), reactance/height (DS: 36.4 ± 5.0; non-DS: 41.9 ± 4.9 Ω/m) and impedance/height (DS: 334.1 ± 51.2; non-DS: 351.4 ± 57.6 Ω/m), while men with DS showed lower phase angle (DS: 6.4 ± 0.7; non-DS: 7.0° ± 0.5°) and lower bioimpedance index (DS: 50.8 ± 6.1; non-DS: 55.2 ± 6.5 Ω/m²); men and women with DS had higher total body water (males p = 0.030; females p = 0.006) and intracellular water (males p = 0.020; females p = 0.010) compared with individuals without DS; women had lower extracellular water (males p = 0.090; females p = 0.004) compared with individuals without DS; the bioelectrical vectors for individuals with DS were different from the population ellipses (p < 0.050), and showed overhydration compared with non-DS.

Conclusions

Adults with DS showed a distinct hydration pattern in comparison with non-DS adults, as shown in BIA and BIVA analysis.

查看原文本刊更多论文

成人唐氏综合症患者的生物阻抗参数会改变吗？横断面研究。

背景：唐氏综合征（DS）患者表现出身体成分的改变，可以通过生物电阻抗分析（BIA）来评估。本研究旨在比较DS患者和非DS患者的BIA测量和生物电阻抗矢量分析（BIVA）。方法：通过BIA和BIVA对46例DS患者和46例非DS患者进行评估。我们采用广义线性模型（GLM）评估群体和性别对BIA的影响，并根据年龄和身高进行调整。结果：DS患者全身阻力/身高（DS: 332.1±51.1；非DS: 349.0±57.5 Ω/m）、电抗/身高（DS: 36.4±5.0；非DS: 41.9±4.9 Ω/m）和阻抗/身高（DS: 334.1±51.2；非DS: 351.4±57.6 Ω/m）较低，男性DS相位角（DS: 6.4±0.7；非DS: 7.0°±0.5°）较低，生物阻抗指数（DS: 50.8±6.1；非DS: 55.2±6.5 Ω/m2）较低；与非DS个体相比，DS患者体内总水分（男性p = 0.030，女性p = 0.006）和细胞内水分（男性p = 0.020，女性p = 0.010）均较高；与没有DS的个体相比，女性的细胞外水较低（男性p = 0.090，女性p = 0.004）；结论：BIA和BIVA分析显示，与非DS成人相比，DS成人的水化模式明显不同。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Intellectual Disability Research Multiple-

CiteScore

5.60

自引率

5.60%

发文量

期刊介绍： The Journal of Intellectual Disability Research is devoted exclusively to the scientific study of intellectual disability and publishes papers reporting original observations in this field. The subject matter is broad and includes, but is not restricted to, findings from biological, educational, genetic, medical, psychiatric, psychological and sociological studies, and ethical, philosophical, and legal contributions that increase knowledge on the treatment and prevention of intellectual disability and of associated impairments and disabilities, and/or inform public policy and practice. Expert reviews on themes in which recent research has produced notable advances will be included. Such reviews will normally be by invitation.