Reframing diet assessment for geroscience: development and preliminary validation of an anti-aging dietary score.

IF 9.7 1区农林科学 Q1 FOOD SCIENCE & TECHNOLOGY

NPJ Science of Food Pub Date : 2026-06-22 DOI:10.1038/s41538-026-00960-y

Shixing Feng, Tianyi Wang, Jinlong Yan, Chaohui Yin, Baoyan Chen, Miao Shi, Jialin Liu, Huaqiang Zhai

引用次数: 0

Abstract

Conventional dietary indices often fail to align with aging biology. To bridge this mechanistic gap, we propose the Nutrient-Signaling-Senescence (NSS) axis as an integrative framework. Based on this foundation, we develop the anti-aging dietary score (AADS). Preliminary validation using NHANES data demonstrates that a higher AADS is significantly associated with lower PhenoAge acceleration, performing comparably to established indices. This framework enables translating aging biology into population-based research.

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重新构建饮食评估的老年科学：抗衰老饮食评分的发展和初步验证。

传统的饮食指标往往不能与衰老生物学相一致。为了弥补这一机制上的差距，我们提出了营养-信号-衰老（NSS）轴作为一个综合框架。在此基础上，我们开发了抗衰老膳食评分（AADS）。使用NHANES数据进行的初步验证表明，较高的AADS与较低的表型加速显著相关，与已建立的指标相当。这个框架能够将衰老生物学转化为基于人口的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

NPJ Science of Food FOOD SCIENCE & TECHNOLOGY-

CiteScore

7.50

自引率

1.60%

发文量

期刊介绍： npj Science of Food is an online-only and open access journal publishes high-quality, high-impact papers related to food safety, security, integrated production, processing and packaging, the changes and interactions of food components, and the influence on health and wellness properties of food. The journal will support fundamental studies that advance the science of food beyond the classic focus on processing, thereby addressing basic inquiries around food from the public and industry. It will also support research that might result in innovation of technologies and products that are public-friendly while promoting the United Nations sustainable development goals.