{"title":"Clinical and Radiological Trajectories at the End of Life in Patients with Bone and Soft Tissue Sarcoma: A Retrospective Case Series.","authors":"Kumiko Yotsuya, Yoji Shido, Yukihiro Matsuyama","doi":"10.1177/10966218261460512","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To provide detailed characteristics of advanced malignant bone and soft tissue tumors at the end of life.</p><p><strong>Design: </strong>A retrospective case series analysis.</p><p><strong>Subject: </strong>We included 24 patients who presented to our department between 2014 and 2024, were diagnosed with malignant bone or soft tissue tumors, and died from tumor-related causes.</p><p><strong>Results: </strong>The mean age was 57.8 ± 15.6 years at death. Acute-onset events requiring emergency admission within three months before death occurred in 91.7%. The reasons for emergency admission included dyspnea due to malignant pleural effusion, sepsis, paraplegia, gastrointestinal bleeding, bone marrow dysfunction, difficulty moving due to pain, acute renal failure, and pulmonary thromboembolism.</p><p><strong>Conclusions: </strong>Patients with advanced sarcoma experience an exceptionally high rate of acute-onset events and emergency admissions in their final months. Emergency hospitalization provides an opportunity to consider transitioning to palliative care.</p>","PeriodicalId":16656,"journal":{"name":"Journal of palliative medicine","volume":" ","pages":"1572-1577"},"PeriodicalIF":1.8000,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of palliative medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/10966218261460512","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/6/12 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: To provide detailed characteristics of advanced malignant bone and soft tissue tumors at the end of life.
Design: A retrospective case series analysis.
Subject: We included 24 patients who presented to our department between 2014 and 2024, were diagnosed with malignant bone or soft tissue tumors, and died from tumor-related causes.
Results: The mean age was 57.8 ± 15.6 years at death. Acute-onset events requiring emergency admission within three months before death occurred in 91.7%. The reasons for emergency admission included dyspnea due to malignant pleural effusion, sepsis, paraplegia, gastrointestinal bleeding, bone marrow dysfunction, difficulty moving due to pain, acute renal failure, and pulmonary thromboembolism.
Conclusions: Patients with advanced sarcoma experience an exceptionally high rate of acute-onset events and emergency admissions in their final months. Emergency hospitalization provides an opportunity to consider transitioning to palliative care.
期刊介绍：
Journal of Palliative Medicine is the premier peer-reviewed journal covering medical, psychosocial, policy, and legal issues in end-of-life care and relief of suffering for patients with intractable pain. The Journal presents essential information for professionals in hospice/palliative medicine, focusing on improving quality of life for patients and their families, and the latest developments in drug and non-drug treatments.
The companion biweekly eNewsletter, Briefings in Palliative Medicine, delivers the latest breaking news and information to keep clinicians and health care providers continuously updated.
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