Gang Li;Atharva Paralikar;Pavel Yarmolenko;Ayush Nankani;Wolfgang Loew;Charles Dumoulin;Kevin Cleary;Chima Oluigbo;Reza Monfaredi
{"title":"A Pneumatically Actuated Robotic Assistant for MRI-Guided Stereotactic Neurosurgery","authors":"Gang Li;Atharva Paralikar;Pavel Yarmolenko;Ayush Nankani;Wolfgang Loew;Charles Dumoulin;Kevin Cleary;Chima Oluigbo;Reza Monfaredi","doi":"10.1109/TMRB.2026.3680983","DOIUrl":null,"url":null,"abstract":"This paper presents the development and cadaveric evaluation of a pneumatically actuated robotic assistant for MRI-guided stereotactic neurosurgery. The robot features two coaxial arcs that provide four degrees of freedom to position and orient a needle within an MRI scanner. It is driven by custom-designed MR-Safe pneumatic stepper motors and powered by in-room compressed medical air, enabling precise interventions under intraoperative MRI guidance. To improve anatomical visualization, two custom MR imaging coils were developed and integrated with the system. A dedicated clinical workflow was also proposed for robot-assisted stereotactic procedures under MRI-guidance. Targeting accuracy was first assessed in free space using an optical tracking system, yielding mean absolute errors of <inline-formula> <tex-math>$0.97 \\pm 0.42$ </tex-math></inline-formula> mm for tip position and <inline-formula> <tex-math>$0.46 \\pm 0.23^{\\circ } $ </tex-math></inline-formula> for needle angle. System-level accuracy was then evaluated in MRI-guided phantom studies, showing errors of <inline-formula> <tex-math>$1.38 \\pm 0.80$ </tex-math></inline-formula> mm in tip position and <inline-formula> <tex-math>$1.08 \\pm 0.67^{\\circ } $ </tex-math></inline-formula> in angle. Finally, a cadaver study validated the clinical workflow, with observed errors of 2.11 mm in position and 3.32° in angle. Quantitative imaging analysis confirmed minimal image degradation, with signal-to-noise ratio (SNR) variation below 12.26% and 2D geometric distortion under 0.20%.","PeriodicalId":73318,"journal":{"name":"IEEE transactions on medical robotics and bionics","volume":"8 2","pages":"906-917"},"PeriodicalIF":4.3000,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE transactions on medical robotics and bionics","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/11475210/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/4/6 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
This paper presents the development and cadaveric evaluation of a pneumatically actuated robotic assistant for MRI-guided stereotactic neurosurgery. The robot features two coaxial arcs that provide four degrees of freedom to position and orient a needle within an MRI scanner. It is driven by custom-designed MR-Safe pneumatic stepper motors and powered by in-room compressed medical air, enabling precise interventions under intraoperative MRI guidance. To improve anatomical visualization, two custom MR imaging coils were developed and integrated with the system. A dedicated clinical workflow was also proposed for robot-assisted stereotactic procedures under MRI-guidance. Targeting accuracy was first assessed in free space using an optical tracking system, yielding mean absolute errors of $0.97 \pm 0.42$ mm for tip position and $0.46 \pm 0.23^{\circ } $ for needle angle. System-level accuracy was then evaluated in MRI-guided phantom studies, showing errors of $1.38 \pm 0.80$ mm in tip position and $1.08 \pm 0.67^{\circ } $ in angle. Finally, a cadaver study validated the clinical workflow, with observed errors of 2.11 mm in position and 3.32° in angle. Quantitative imaging analysis confirmed minimal image degradation, with signal-to-noise ratio (SNR) variation below 12.26% and 2D geometric distortion under 0.20%.